ID S2JEU9_MUCC1 Unreviewed; 537 AA.
AC S2JEU9;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=SPX domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF1544_12264 {ECO:0000313|EMBL:EPB81038.1};
OS Mucor circinelloides f. circinelloides (strain 1006PhL) (Mucormycosis
OS agent) (Calyptromyces circinelloides).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=1220926 {ECO:0000313|EMBL:EPB81038.1, ECO:0000313|Proteomes:UP000014254};
RN [1] {ECO:0000313|Proteomes:UP000014254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1006PhL {ECO:0000313|Proteomes:UP000014254};
RG The Broad Institute Genomics Platform;
RA Cuomo C., Earl A., Findley K., Lee S.C., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome sequence of Mucor circinelloides f. circinelloides 1006PhL.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KE124221; EPB81038.1; -; Genomic_DNA.
DR AlphaFoldDB; S2JEU9; -.
DR STRING; 1220926.S2JEU9; -.
DR VEuPathDB; FungiDB:HMPREF1544_12264; -.
DR eggNOG; KOG4159; Eukaryota.
DR InParanoid; S2JEU9; -.
DR OMA; PYLIQYK; -.
DR OrthoDB; 3904425at2759; -.
DR Proteomes; UP000014254; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd23137; RING-HC_TRY3-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR004331; SPX_dom.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR23327; RING FINGER PROTEIN 127; 1.
DR PANTHER; PTHR23327:SF50; TRANSCRIPTIONAL REGULATOR OF YEAST FORM ADHERENCE 3; 1.
DR Pfam; PF03105; SPX; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51382; SPX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000014254};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 1..389
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT DOMAIN 425..464
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 134..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 190..224
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 143..163
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 537 AA; 62126 MW; C55C59195A42FD71 CRC64;
MKFGKQLETE AEGIPSEWRP YLIQYKALKK LITKVAEEIE SRGLSTSLLH ECLEEDGGLP
SVNDEEGESI PKIKYYFTGE PPNVKPNIEF TYDSKEPKVQ KVLEKLFSSS PLATDHVERP
KLEFKRSHNN KDFFSLSTAT DDDSSANDKD ADQHDETTLD NQEQQQQEER IVIKSPAVIR
QRRSSTVALV KELLALTLEE KDRIKDAEKE DQETEEVQEK HEKHIKTLVI ELEQDDEFFK
MLMEELQQAA MLQDVTSQKF QHDISDLETR MTKVAAPTQK TDMYNWRKIF SIYMDAQIFQ
GNAESDRTFR SVERAKKQMT WFVEQLGKSN LLNKLKSKES RCAFEQFIAL NTELITMKHY
QMLNETAMRK ILKKHDKRSG LTASQSFPEI VSTEALFSPK LAKMLYSTIT TKLTTIIPQP
EDYACPVCMS VAWRPIRLAC SHVFCVRCLI KAQKKKMDSC PLCRHPTAVK SATALNLDEG
LQNFLKLYFP QEIKEKKREN EREQAIEDVQ AMTGKKYTEE QLMRMSQNHS DSKCNIM
//
