ID S2JFV6_MUCC1 Unreviewed; 1200 AA.
AC S2JFV6;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=SH3 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF1544_05788 {ECO:0000313|EMBL:EPB87362.1};
OS Mucor circinelloides f. circinelloides (strain 1006PhL) (Mucormycosis
OS agent) (Calyptromyces circinelloides).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=1220926 {ECO:0000313|EMBL:EPB87362.1, ECO:0000313|Proteomes:UP000014254};
RN [1] {ECO:0000313|Proteomes:UP000014254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1006PhL {ECO:0000313|Proteomes:UP000014254};
RG The Broad Institute Genomics Platform;
RA Cuomo C., Earl A., Findley K., Lee S.C., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome sequence of Mucor circinelloides f. circinelloides 1006PhL.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KE123969; EPB87362.1; -; Genomic_DNA.
DR AlphaFoldDB; S2JFV6; -.
DR STRING; 1220926.S2JFV6; -.
DR VEuPathDB; FungiDB:HMPREF1544_05788; -.
DR eggNOG; KOG2398; Eukaryota.
DR InParanoid; S2JFV6; -.
DR OMA; IMMARSI; -.
DR OrthoDB; 2025446at2759; -.
DR Proteomes; UP000014254; Unassembled WGS sequence.
DR GO; GO:0030864; C:cortical actin cytoskeleton; IEA:UniProt.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:UniProt.
DR CDD; cd00174; SH3; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23065:SF7; CYTOKINESIS PROTEIN 2; 1.
DR PANTHER; PTHR23065; PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077};
KW Reference proteome {ECO:0000313|Proteomes:UP000014254};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 28..285
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 1130..1194
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 355..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 423..480
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 492..562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 686..739
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 762..822
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 913..1122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 355..381
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..446
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..480
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 492..528
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..562
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 686..708
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 723..739
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 762..792
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 939..971
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1012..1035
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1047..1121
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1200 AA; 133418 MW; 1E7EC8FB01D59FE2 CRC64;
MASGISHPQQ QHQQHQQQQQ QTSNNTGINF KDAFWDDQNK GVEILSSRLR KSKDTCEELK
KLYQLRASIE QDYGERLLKL AQTSRIGEFE ENSFAETLSR IPSALETTAR AHIDLAQQLQ
DHLEVPLDGF LKDQRDVRKM QQQHIENSKQ LKNLHEADVA RAKDYCLSEY NKLRSMEAYR
SELSNGSTDD IAKIEKEIDE QKRMVAVADQ VYKRSVDNYN AVNDKWVNDW SSTADVYQEM
EVKRISYLRS TLWSFANMMT ITFSIDEECC DRIRTALEIT DVQKDVTAFV QRYGTGNRIP
APMQYEALYD ASHVQTTMPT SAVNKSSAPV MATAVGVAAA APATIGTMAA VSNLSNSDQP
LSAPLPKTSS SANSLSDATP RGASESAAAA KKLPPHPPVT ILTNPDEELK SVDRQLRQLE
VQNTTPQSEN ENHQFNIMTS PQQLTSADVD EKREIVDKEQ QQPPLSGVTN TTDQSNGPVS
TAMKEVEQIL NQKNNSQDAV ATTATAETAT SKNRESYASS SHTDNGPKQS LPPIMMARSI
PPSAAAGKTA SPTASNRPVS DDFSGSIYNA LGMKEEPATS QYDLHKEQSD SVTKSNSAVE
LAPLSSETHI LMPFDTLATR NESTISNGSG KDMNQKYKPM PNPIYNSNGA MIAAKDIPPS
KNEMNYAAPE TVPNMKPVVG VRTSSLLLSQ KPSSPQNGSR TSSLNREMIN NKNDEDDYED
NEDEKEYHNR MPRPPPKDER WVISSIRRPQ QLPVRTMNAK MFDGTTSSRN SMASPTPPPI
VSASSAEHSP AADLNTSPAA GADNVEDDIH RHPKPHRPAI PLTIDIPNSV KPASDVAQNA
AQQVIAEGKR RSQMSPVQQN MDLHQQPQSQ PQTMDRNVIR GYINNQQNGM EEGGIRPAPW
QEEFNNDDHR VMRAPMPNNG SGYYSNGHAG YQPGMPGPRS SSIKLSEQQQ QQQQQQQQML
MQQQQQQQQQ QHFEEETKKR FGKNAKQFSG ESSVKSKEKE NKTGRFSLGF FGGGKKEKKK
EKEKEKEKEK EKESAAAAAA AAAAMYTQQP PDSSYMQQQQ QQPYMQQQPR PLSQQQMYQK
QPSLHELSQS DLKSNHSGQQ QQHTPQAQQQ ATQQQLPQPQ LVKAPLSADR FIGFAKAQWP
FEATIDGEMS FQADEVVGII HKQMDGWWEA ERLGPVGAGQ RGLVPGNYML DNQPPPPSLQ
//
