ID S2KAP0_MUCC1 Unreviewed; 691 AA.
AC S2KAP0;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Glycogen [starch] synthase {ECO:0000256|RuleBase:RU363104};
DE EC=2.4.1.11 {ECO:0000256|RuleBase:RU363104};
GN ORFNames=HMPREF1544_03739 {ECO:0000313|EMBL:EPB89370.1};
OS Mucor circinelloides f. circinelloides (strain 1006PhL) (Mucormycosis
OS agent) (Calyptromyces circinelloides).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=1220926 {ECO:0000313|EMBL:EPB89370.1, ECO:0000313|Proteomes:UP000014254};
RN [1] {ECO:0000313|Proteomes:UP000014254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1006PhL {ECO:0000313|Proteomes:UP000014254};
RG The Broad Institute Genomics Platform;
RA Cuomo C., Earl A., Findley K., Lee S.C., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome sequence of Mucor circinelloides f. circinelloides 1006PhL.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transfers the glycosyl residue from UDP-Glc to the non-
CC reducing end of alpha-1,4-glucan. {ECO:0000256|RuleBase:RU363104}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-
CC alpha-D-glucosyl](n+1) + H(+) + UDP; Xref=Rhea:RHEA:18549, Rhea:RHEA-
CC COMP:9584, Rhea:RHEA-COMP:9587, ChEBI:CHEBI:15378, ChEBI:CHEBI:15444,
CC ChEBI:CHEBI:58223, ChEBI:CHEBI:58885; EC=2.4.1.11;
CC Evidence={ECO:0000256|ARBA:ARBA00043769};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:18550;
CC Evidence={ECO:0000256|ARBA:ARBA00043769};
CC -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004964, ECO:0000256|RuleBase:RU363104}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 3 family.
CC {ECO:0000256|ARBA:ARBA00010686, ECO:0000256|RuleBase:RU363104}.
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DR EMBL; KE123935; EPB89370.1; -; Genomic_DNA.
DR AlphaFoldDB; S2KAP0; -.
DR STRING; 1220926.S2KAP0; -.
DR VEuPathDB; FungiDB:HMPREF1544_03739; -.
DR eggNOG; KOG3742; Eukaryota.
DR InParanoid; S2KAP0; -.
DR OMA; RMHKSNV; -.
DR OrthoDB; 9432at2759; -.
DR UniPathway; UPA00164; -.
DR Proteomes; UP000014254; Unassembled WGS sequence.
DR GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 6.10.260.10; -; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR008631; Glycogen_synth.
DR PANTHER; PTHR10176:SF3; GLYCOGEN [STARCH] SYNTHASE; 1.
DR PANTHER; PTHR10176; GLYCOGEN SYNTHASE; 1.
DR Pfam; PF05693; Glycogen_syn; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Glycogen biosynthesis {ECO:0000256|ARBA:ARBA00023056,
KW ECO:0000256|RuleBase:RU363104};
KW Glycosyltransferase {ECO:0000256|RuleBase:RU363104};
KW Reference proteome {ECO:0000313|Proteomes:UP000014254};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363104}.
SQ SEQUENCE 691 AA; 79320 MW; 8E513120CD6EB5A6 CRC64;
MTTVQRDVYN PLLFEIAWEV ANKVGGIYTV IKTKVPVTVR EFGDRYTLIG PLSYKTAPME
VEACEPANEK MKEVLDSMSQ YGVKYLYGRW LVEGSPYVLL FDTGSVLNKL DEWKGDLWRS
AGIPSPPHDT ETNDAILFGY LVTWFLGELT PKYNKSGDPA IICHFHEWLA GVAVPLIKKR
HLDVCTIFTT HATLLGRYLC AGSVDFYNNL ANFDVDEEAG KRGIYHRYCI ERGAAHCADV
FTTVSHITAY ESEHLLKRKP DGVLPNGLNV VKFSAMHEFQ NLHALSKEKI NDFVRGHFYG
HYDFDLDNTI YIFTAGRYEY RNKGVDMFVE SLARLNARLK SSGSKMTVVA FLIMPTATHS
FNVEALKGQA VTRQLRTTVS EIQDRVGKAI YENALRLEDI NPTNFLSDAD KVLLKRRVFA
LKRTTLPPIV THNIVDDSKD PVLNQLRRLN MFNNSDDRVK IVFHPEFLNA NNPLIGMDYE
EFVRGCHLGV FPSYYEPWGY TPAECTVMGV PSITTNLSGF GCFMEENIEN CDDYGIYITD
RRMKSVEDSL QQLCDQMYQF VQKTRRQRIN QRNRTERLSD LLDWKRMGLE YIKARQLALR
RAYPDSFIDD DEEELLSDAP VKIPKPLSAP ASPRLRMEVN NMFNDDEEEE DFLFPALRRK
NQVQTREQEL LSEGDIEAFN KLTLENKEAH H
//
