ID   S2Z168_9ACTN            Unreviewed;       440 AA.
AC   S2Z168;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   RecName: Full=Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=HMPREF1211_02859 {ECO:0000313|EMBL:EPD63732.1};
OS   Streptomyces sp. HGB0020.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1078086 {ECO:0000313|EMBL:EPD63732.1, ECO:0000313|Proteomes:UP000014410};
RN   [1] {ECO:0000313|EMBL:EPD63732.1, ECO:0000313|Proteomes:UP000014410}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HGB0020 {ECO:0000313|EMBL:EPD63732.1,
RC   ECO:0000313|Proteomes:UP000014410};
RG   The Broad Institute Genomics Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Schmidt T.M., Dai D., Dover J.,
RA   Kim K., Walker B., Young S., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Allen A.W., Alvarado L., Arachchi H.M., Berlin A.M.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA   Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Streptomyces sp. HGB0020.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EPD63732.1}.
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DR   EMBL; AGER01000012; EPD63732.1; -; Genomic_DNA.
DR   AlphaFoldDB; S2Z168; -.
DR   STRING; 1078086.HMPREF1211_02859; -.
DR   PATRIC; fig|1078086.3.peg.2896; -.
DR   HOGENOM; CLU_636023_0_0_11; -.
DR   Proteomes; UP000014410; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd03386; PAP2_Aur1_like; 1.
DR   InterPro; IPR026841; Aur1/Ipt1.
DR   InterPro; IPR045977; DUF5933.
DR   PANTHER; PTHR31310; -; 1.
DR   PANTHER; PTHR31310:SF7; PA-PHOSPHATASE RELATED-FAMILY PROTEIN DDB_G0268928; 1.
DR   Pfam; PF19356; DUF5933; 1.
DR   Pfam; PF14378; PAP2_3; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014410};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        60..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        90..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        218..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        316..336
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        366..386
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        398..416
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          2..140
FT                   /note="DUF5933"
FT                   /evidence="ECO:0000259|Pfam:PF19356"
FT   DOMAIN          180..353
FT                   /note="Inositolphosphotransferase Aur1/Ipt1"
FT                   /evidence="ECO:0000259|Pfam:PF14378"
SQ   SEQUENCE   440 AA;  48070 MW;  33716B06E1AB940F CRC64;
     MVAIAVIGFL MALELAARHY GQPGPLTTQA RELIFPPKSG GVLYAGLALM MVVLTWRQRF
     IALGAAIGID VVFSLIRWTA DIRVTDGHPF GNGALWVILG CAVIAVARRT GPDRVLLLKG
     VGLALLLVTG RKTGDAWLFI TAKTRPMVLD QYVATTDHAL GNPSWLLGRL VTACGPVGFN
     FLDIVYGQLP VAAVAVALYQ LRHVAAERRF PRHHLVRTFL VIGLVGPVFY MIFPVVGPLF
     AYGTGAQHWE GVSLWAPHMA PSAQWAAADL WPRTLPPIGV PHHMPFDHIT PRNCMPSLHT
     AWATAIFIHS RKGPRALRHA GTFWLIATLT ATLGFGYHYG ADLIAGVVFT LTIEAALRAY
     DHGWDWSGIH LVTYGATVFT ALLLSYRYRP VEMALHPWLS GPLLLLALAS VIYAYVRTTT
     AWDAGTLPTR RPTAPQPELI
//