ID S2ZY62_9ACTN Unreviewed; 607 AA.
AC S2ZY62;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Beta-galactosidase {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF1211_00545 {ECO:0000313|EMBL:EPD69029.1};
OS Streptomyces sp. HGB0020.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1078086 {ECO:0000313|EMBL:EPD69029.1, ECO:0000313|Proteomes:UP000014410};
RN [1] {ECO:0000313|EMBL:EPD69029.1, ECO:0000313|Proteomes:UP000014410}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HGB0020 {ECO:0000313|EMBL:EPD69029.1,
RC ECO:0000313|Proteomes:UP000014410};
RG The Broad Institute Genomics Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Schmidt T.M., Dai D., Dover J.,
RA Kim K., Walker B., Young S., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Allen A.W., Alvarado L., Arachchi H.M., Berlin A.M.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Streptomyces sp. HGB0020.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPD69029.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGER01000002; EPD69029.1; -; Genomic_DNA.
DR RefSeq; WP_016430521.1; NZ_KE150426.1.
DR AlphaFoldDB; S2ZY62; -.
DR STRING; 1078086.HMPREF1211_00545; -.
DR PATRIC; fig|1078086.3.peg.554; -.
DR HOGENOM; CLU_009935_2_1_11; -.
DR OrthoDB; 9762066at2; -.
DR Proteomes; UP000014410; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR42732:SF3; BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000014410}.
FT DOMAIN 27..180
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 192..288
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 326..458
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 607 AA; 68510 MW; B88223EF6FE9DC8D CRC64;
MPSPRPSDPP RPEYPRPQFV REAWLNLNGE WQFEIDRSDT GLERGLRERE LDDRIVVPFC
PESTLSGIGE TDFLEAVWYR RTVTVPEDWA DSRVLLHFGA VDHDTTVWAD GVEVARHRGG
FTPFTADLGE VAVAGRELTL VVRARDSRHG VQARGKQATW YANSHCHYTR TTGIWQTVWL
EPVPRAAALG RPRITPDLAS GSFHLELPLT ANLPGHRVRA TLADDRGEIL TAETRADLDL
APRLVLPVPA DRLRPWSPAD PHLYDLTLQL LGADGQIVDT ATSYAGLRSV SVRGKRLLLN
GEPVFQRLVL DQGYYPDGLM TAPTDADLVR DIELGLRAGF NGARLHQKVF EERYLYHADR
LGYLVWGEFG DWGCETGVRD DNQRPDASYV TQWLEALERD YSHPSIVGWC PLNETYQPLH
DRITRLDDVT RAMFLATKQA DATRPVIDAS GYAHRIAETD VYDSHCYEQD PAAFAKAMSG
LAENRPYVNA APDGRPWSVP YRGQPYFCSE FGGIWWDPEA AAAAGDQRDA SWGYGERPYT
EEEFIERFAG LTAVLLDDAD MFGYCYTQLT DVFQERNGVY RFNRSEKLDT ARLHRAQTRP
AAYENTP
//
