ID S3CG54_GLAL2 Unreviewed; 499 AA.
AC S3CG54;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPE24234.1};
GN ORFNames=GLAREA_08084 {ECO:0000313|EMBL:EPE24234.1};
OS Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiaceae; Glarea.
OX NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE24234.1, ECO:0000313|Proteomes:UP000016922};
RN [1] {ECO:0000313|EMBL:EPE24234.1, ECO:0000313|Proteomes:UP000016922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT the fungus Glarea lozoyensis.";
RL BMC Genomics 14:339-339(2013).
CC -!- SIMILARITY: Belongs to the beclin family.
CC {ECO:0000256|ARBA:ARBA00005965}.
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DR EMBL; KE145373; EPE24234.1; -; Genomic_DNA.
DR RefSeq; XP_008088322.1; XM_008090131.1.
DR AlphaFoldDB; S3CG54; -.
DR STRING; 1116229.S3CG54; -.
DR GeneID; 19467135; -.
DR KEGG; glz:GLAREA_08084; -.
DR eggNOG; KOG2751; Eukaryota.
DR HOGENOM; CLU_024219_3_1_1; -.
DR OMA; EWDVYKA; -.
DR OrthoDB; 11439at2759; -.
DR Proteomes; UP000016922; Unassembled WGS sequence.
DR GO; GO:0006914; P:autophagy; IEA:InterPro.
DR Gene3D; 6.10.250.3110; -; 1.
DR Gene3D; 1.10.418.40; Autophagy protein 6/Beclin 1; 1.
DR InterPro; IPR007243; Atg6/Beclin.
DR InterPro; IPR038274; Atg6/Beclin_C_sf.
DR InterPro; IPR041691; Atg6/beclin_CC.
DR InterPro; IPR040455; Atg6_BARA.
DR PANTHER; PTHR12768; BECLIN 1; 1.
DR PANTHER; PTHR12768:SF4; BECLIN-1; 1.
DR Pfam; PF04111; APG6; 1.
DR Pfam; PF17675; APG6_N; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000016922}.
FT DOMAIN 159..287
FT /note="Atg6/beclin coiled-coil"
FT /evidence="ECO:0000259|Pfam:PF17675"
FT DOMAIN 290..489
FT /note="Atg6 BARA"
FT /evidence="ECO:0000259|Pfam:PF04111"
FT REGION 30..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 102..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 162..251
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 48..74
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 111..133
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 499 AA; 56297 MW; A9392383ADC45C3C CRC64;
MHCQKCRKPL KLDGSLDDLN PAAFDLLVGA SQQPPKNIPS SRPAYPQERK QLYDRVSKDA
KSPTFKRHTS NPRRSDASSS EYRQGLTNPA MSFVMLTESQ VVPPSIIKSP EDTNPKRRAH
DDGKNLDGGD DEGKAMSQEM ERVSRLFEIL SARSDIDHPV CVECTEMLVD GLQRRLEAHT
RERDAYSGYL KEVHASVPTE EEVKESQEQL AKARADEANA VEELKKLEKE KAAVDNEILV
LEQEARALDL EEEEFWRERN AFTAKLTEFQ NIRDSVNQQF DHDSQLLEKL QRTNVYNDTF
CISHDGKFGT INGLRLGRLS NVTVDWQEIN AAWGHTLLLL ATVAEKLSFK FTGYDLQPMG
STSRIIRYDN VSPSTSRTSS TRSTRPPTKK ILELYSSGDM PLGLTFMHRK FDTAMVAFLA
CMKQLGDFVE QESSRGHEEG KGLCLPYKID GDRIGDVSIK LGIAQDDAWS RACKFTLTCC
KFLLAHASNL NVMNNRRGN
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