ID S3CNN5_GLAL2 Unreviewed; 673 AA.
AC S3CNN5;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=GTPase activation, GAP {ECO:0000313|EMBL:EPE28127.1};
GN ORFNames=GLAREA_04918 {ECO:0000313|EMBL:EPE28127.1};
OS Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiaceae; Glarea.
OX NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE28127.1, ECO:0000313|Proteomes:UP000016922};
RN [1] {ECO:0000313|EMBL:EPE28127.1, ECO:0000313|Proteomes:UP000016922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT the fungus Glarea lozoyensis.";
RL BMC Genomics 14:339-339(2013).
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DR EMBL; KE145369; EPE28127.1; -; Genomic_DNA.
DR RefSeq; XP_008085486.1; XM_008087295.1.
DR AlphaFoldDB; S3CNN5; -.
DR STRING; 1116229.S3CNN5; -.
DR GeneID; 19463973; -.
DR KEGG; glz:GLAREA_04918; -.
DR eggNOG; KOG4269; Eukaryota.
DR HOGENOM; CLU_017095_1_0_1; -.
DR OMA; DEQYDVN; -.
DR OrthoDB; 1359393at2759; -.
DR Proteomes; UP000016922; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23176:SF125; GTPASE ACTIVATOR (BEM2), PUTATIVE (AFU_ORTHOLOGUE AFUA_7G04450)-RELATED; 1.
DR PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016922}.
FT DOMAIN 378..575
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 572..673
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..92
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 108..129
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 130..160
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..193
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..243
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..285
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..326
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 579..593
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 600..651
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 673 AA; 75314 MW; DB8E8D7EEAF6E7E1 CRC64;
MARKSHPQPL TLTDPRLVGD QDFLNNPRSP LSPTSPKSPR SPFRFSTKKA QAEGEQPPMQ
SSDSQRTRNT LPPTQNSVSL PSLDSFTSAQ PSDRVEADKE QRPARSGFFS NYKASKSSSR
LQANQDGSRQ DDNMSKDAER PKVSSQETSR SDRSTDRSTK RKPVGGGPSR SEVSIDSTSD
AGTPSSSNVN KKSKPKAFGL LSRTRSIRDE NSPREPSPTD KLQPPQQPER NHQHAYSESI
KTAPLRSDND RTFRDMMGSS VRQHSEDRQT SRARDASREK APREPSKLQP SLMRDTSKEN
KIPTFSSAPQ EKSGHGFLNN LRSSATKGAG AIHKGLFGKG GRSGSTNEKE QPVDDEHYEL
KVINKPLVEQ TRLTRISKRL EDSRDKTEFW MPAFPWRAID YLNYKGSDVE GLYRVPGSGP
QIKKWQRRFD EEMDIDLFEQ DDLYDINIIG SMLKAWLREL PDELFPKSAQ DRIARECVGS
EKVPQQLVDE LSNLSPFNYY LLFAITCHLS LLLAHSAKNK MDFRNLCICF QPCMKIDAFC
FKFLVCDWRD CWKGCKTETQ YTEQEYMLFD MAQVPPPPGS REGQSSTAVE SHDERNVSSS
DSSKPSSVSI DNQGQRKGSA STQPKKSAIG QSHGGGSMST VNTTLTVQDR TPPKRSAEMR
PLSPIKPLSP IGL
//
