ID S3CTC1_GLAL2 Unreviewed; 415 AA.
AC S3CTC1;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Glycosidase {ECO:0000256|PIRNR:PIRNR037299};
DE EC=3.2.-.- {ECO:0000256|PIRNR:PIRNR037299};
GN ORFNames=GLAREA_00053 {ECO:0000313|EMBL:EPE28895.1};
OS Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiaceae; Glarea.
OX NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE28895.1, ECO:0000313|Proteomes:UP000016922};
RN [1] {ECO:0000313|EMBL:EPE28895.1, ECO:0000313|Proteomes:UP000016922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT the fungus Glarea lozoyensis.";
RL BMC Genomics 14:339-339(2013).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 16 family.
CC {ECO:0000256|PIRNR:PIRNR037299}.
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DR EMBL; KE145367; EPE28895.1; -; Genomic_DNA.
DR RefSeq; XP_008083004.1; XM_008084813.1.
DR AlphaFoldDB; S3CTC1; -.
DR GeneID; 19459113; -.
DR KEGG; glz:GLAREA_00053; -.
DR eggNOG; ENOG502QQ71; Eukaryota.
DR HOGENOM; CLU_027506_3_1_1; -.
DR OMA; AQTNYFS; -.
DR OrthoDB; 337487at2759; -.
DR Proteomes; UP000016922; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:UniProtKB-UniRule.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:InterPro.
DR CDD; cd02183; GH16_fungal_CRH1_transglycosylase; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000757; GH16.
DR InterPro; IPR017168; Glyco_hydro_16_CRH1_prd.
DR PANTHER; PTHR10963:SF27; GLYCOSIDASE CRH1-RELATED; 1.
DR PANTHER; PTHR10963; GLYCOSYL HYDROLASE-RELATED; 1.
DR Pfam; PF00722; Glyco_hydro_16; 1.
DR PIRSF; PIRSF037299; Glycosidase_CRH1_prd; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS51762; GH16_2; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR037299-2};
KW Hydrolase {ECO:0000256|PIRNR:PIRNR037299};
KW Lectin {ECO:0000313|EMBL:EPE28895.1};
KW Membrane {ECO:0000256|PIRNR:PIRNR037299};
KW Reference proteome {ECO:0000313|Proteomes:UP000016922};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..415
FT /note="Glycosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004518909"
FT DOMAIN 29..257
FT /note="GH16"
FT /evidence="ECO:0000259|PROSITE:PS51762"
FT REGION 276..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 350..375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 120
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR037299-1"
FT ACT_SITE 124
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR037299-1"
FT DISULFID 26..33
FT /evidence="ECO:0000256|PIRSR:PIRSR037299-2"
SQ SEQUENCE 415 AA; 42286 MW; 458F820604935FF7 CRC64;
MRTSLSAATI FLSALQLATA QTFTDCDPTK KTCPANPGLG GTVETDFTKG KNDAWTYADG
TTINYDPAKG AVFSIAKSTN APTMAFSKYI MFGKVSVVMQ AAPGAGIVSS FILESADLDE
IDWEWIGAVD MDAQSNFFGK GNTSSYDRGA HHAMPVSPGA VNGFHTYEID WNKDAIKWSI
DGNSVRTLPY SSPLALGGQN YPQTPMKVKM GSWVGCASKE AASDPKTQGT CEWASGPADF
ASGPFDMYVK SVTIQDYGCG GDYTYSDMTG SYQSIKSSGK CDGNANTVVS SSESVPAITG
SATGSVTSTG SAVSTSVSTT AKSSSASASA SASGSSTLTS AVKEATQAAA ANGTGTVRPS
LNTAVSPVPT GPSASASNAA AAATAASGAS RPSHKYGAMD IGVMVLGLGL GYLVM
//
