ID   S3CTL8_GLAL2            Unreviewed;       960 AA.
AC   S3CTL8;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Magnesium transport protein CorA, transmembrane region {ECO:0000313|EMBL:EPE28369.1};
GN   ORFNames=GLAREA_09489 {ECO:0000313|EMBL:EPE28369.1};
OS   Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Helotiaceae; Glarea.
OX   NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE28369.1, ECO:0000313|Proteomes:UP000016922};
RN   [1] {ECO:0000313|EMBL:EPE28369.1, ECO:0000313|Proteomes:UP000016922}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX   PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA   Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA   Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT   "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT   the fungus Glarea lozoyensis.";
RL   BMC Genomics 14:339-339(2013).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; KE145368; EPE28369.1; -; Genomic_DNA.
DR   RefSeq; XP_008084277.1; XM_008086086.1.
DR   AlphaFoldDB; S3CTL8; -.
DR   GeneID; 19468537; -.
DR   KEGG; glz:GLAREA_09489; -.
DR   eggNOG; KOG4177; Eukaryota.
DR   HOGENOM; CLU_006096_0_0_1; -.
DR   OMA; IRYFHIP; -.
DR   OrthoDB; 2331393at2759; -.
DR   Proteomes; UP000016922; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015693; P:magnesium ion transport; IEA:UniProt.
DR   Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 1.
DR   InterPro; IPR045863; CorA_TM1_TM2.
DR   InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR   PANTHER; PTHR47685; MAGNESIUM TRANSPORT PROTEIN CORA; 1.
DR   PANTHER; PTHR47685:SF1; MAGNESIUM TRANSPORT PROTEIN CORA; 1.
DR   Pfam; PF01544; CorA; 1.
DR   SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016922};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        765..787
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        808..829
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        835..857
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          656..675
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        659..675
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   960 AA;  111262 MW;  FC385CC986B3D7F2 CRC64;
     MIDYSHCQSR VDRLAHGTSP STDNAVLHFF GCLRFEERQS FLDSLDDSDR AKQRIQDENT
     RIQNMRNIFE MEGHNTAAGS LLYRFKVTLG YRFPKLNNLP RPRIDPVPNA RSAEARRNLK
     RAEEREKEFV LEDLNANIIY FKKEKHDQHL QPYDHPKFLP SKFPDQKIKL SQLLKDDSDS
     NPLMWKCEEN MIRYFHLPAN NMEWIEEAIA RYYDERNVQL SGPYQKPRRP EDHSKTRMLL
     RPQYWRGLQH GNHIGLPTHT RHMRPRCYPI STDYQNLEPQ PKNLALFMPY LHWETDRRRA
     RSAEVVRRYG NDRWTPFAEV VDQRHTPVNV SKMKRISSDG FPEHITTIIE AAQGWCGPKK
     ITLKSYQGQT LLGKLLLLAA ALYEELDAYT DEKMVKHYLT SNPPLHPRRT LDQSYYWTLR
     DTRSRDRDQV VYRGTAPPPK LLHHQCRKKA NKDRPCAQCQ ENASKVPRVV MVDQLWMWIL
     DENTVITCFP KRFGRNKPDV SAVQKCIRTR LRAARIDEVR SVYDLAIIII DQCSRVFFDR
     TQSEDLQPQV MDCFGNAIGR VTHKQSIAFD HFWECTRLAS KRYNSRNEPD NGTAKKSQNV
     LLDINPEGDL LREIKDIMDE IFIMMLIKKQ EETVARTFAK HIKPLIKKTA YLSNAADSRT
     SDDDSDSSRR HDDGLLASPV LRQGPKIIIP RSAVSEDYEW TSSSANELVE RIESQLQELK
     YLQDAAENAS LALKDLLSLK QQQAGVVEAR EAVKQGEETL RQGRAIMLFT VITIIFLPMT
     FFLGVFGMNT TELIGDAPGS SNWKYKDVFK FMIPISSVVI TCSLCLAFSK LVRAVLSYAF
     NISWTYFITQ TSLYVTWRDT SLNSKWLHED RKVKVNAMKT RAKQKALEEK MKQARRVAKL
     ESDAKQKREI RIRSGNIASY NIASPITPTM GTAAFDTPRR NQRLRSSDLE MTGAVMQNGG
//