ID S3D491_GLAL2 Unreviewed; 236 AA.
AC S3D491;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Protein YAE1 {ECO:0000256|ARBA:ARBA00018400};
DE AltName: Full=Protein yae1 {ECO:0000256|ARBA:ARBA00017286};
GN ORFNames=GLAREA_12016 {ECO:0000313|EMBL:EPE31934.1};
OS Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiaceae; Glarea.
OX NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE31934.1, ECO:0000313|Proteomes:UP000016922};
RN [1] {ECO:0000313|EMBL:EPE31934.1, ECO:0000313|Proteomes:UP000016922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT the fungus Glarea lozoyensis.";
RL BMC Genomics 14:339-339(2013).
CC -!- FUNCTION: The complex LTO1:YAE1 may function as a target specific
CC adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur
CC protein assembly (CIA) complex machinery. May be required for
CC biogenesis of the large ribosomal subunit and initiation of
CC translation. {ECO:0000256|ARBA:ARBA00003836}.
CC -!- SUBUNIT: May form a complex with LTO1. {ECO:0000256|ARBA:ARBA00011427}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the YAE1 family.
CC {ECO:0000256|ARBA:ARBA00007096}.
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DR EMBL; KE145360; EPE31934.1; -; Genomic_DNA.
DR RefSeq; XP_008080989.1; XM_008082798.1.
DR AlphaFoldDB; S3D491; -.
DR STRING; 1116229.S3D491; -.
DR GeneID; 19471057; -.
DR KEGG; glz:GLAREA_12016; -.
DR eggNOG; KOG4774; Eukaryota.
DR HOGENOM; CLU_066684_0_1_1; -.
DR OMA; MHFQPVE; -.
DR OrthoDB; 2018411at2759; -.
DR Proteomes; UP000016922; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR019191; Essential_protein_Yae1_N.
DR InterPro; IPR038881; Yae1-like.
DR PANTHER; PTHR18829; PROTEIN YAE1 HOMOLOG; 1.
DR PANTHER; PTHR18829:SF0; PROTEIN YAE1 HOMOLOG; 1.
DR Pfam; PF09811; Yae1_N; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000016922}.
FT DOMAIN 66..104
FT /note="Essential protein Yae1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF09811"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 206..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 236 AA; 26394 MW; 04EAE82507D12D69 CRC64;
MFRDDEMYPP PAGSRDDESR EVEDDANDIL DDVFGSEPGS PAFGGGGAND EYSDIPRLRE
KHETEGYRDG VTKGKAETVQ KGFDEGYSLG AVLGLRIGKV LGLLEGVWGG VRSVKDESEV
WDRERARLEV LVKEGREELR TESLFGAEWW GEDGIWKYDV PGEGGEVVWE DVAKAHPLVV
KWEGIVDEEV KRWGLDLKIM DNRRGEDEVA ERDATDKILD TPAQPTTGVQ KKELAW
//
