ID S3D8C0_GLAL2 Unreviewed; 1004 AA.
AC S3D8C0;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=GLAREA_06387 {ECO:0000313|EMBL:EPE33374.1};
OS Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiaceae; Glarea.
OX NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE33374.1, ECO:0000313|Proteomes:UP000016922};
RN [1] {ECO:0000313|EMBL:EPE33374.1, ECO:0000313|Proteomes:UP000016922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT the fungus Glarea lozoyensis.";
RL BMC Genomics 14:339-339(2013).
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DR EMBL; KE145358; EPE33374.1; -; Genomic_DNA.
DR RefSeq; XP_008079991.1; XM_008081800.1.
DR AlphaFoldDB; S3D8C0; -.
DR STRING; 1116229.S3D8C0; -.
DR GeneID; 19465440; -.
DR KEGG; glz:GLAREA_06387; -.
DR eggNOG; KOG0923; Eukaryota.
DR HOGENOM; CLU_001832_7_0_1; -.
DR OMA; HITLMNV; -.
DR OrthoDB; 3682876at2759; -.
DR Proteomes; UP000016922; Unassembled WGS sequence.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EPE33374.1};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000016922}.
FT DOMAIN 373..537
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 559..735
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..26
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..78
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 90..152
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1004 AA; 114055 MW; F4188095AD7D7DEF CRC64;
MGAAKKYALL PMEDDEVGPA KVVEKKERRR HRDKHSSSRH DKRSERSRER SPRRESEHRS
KTIRKREATD ANFEDRWGDE EYVSEEEEPE FVESASKRIK TSHTDEEEDI SDTERERRKD
QEEKDAFAKR LHSKDKDRTK KLVEDRSSTK EGNILAQRRA LAEDAAARSA ALPDLRERSR
QEYLKKREAE RLALLRKQVA EETEELRSGA RLSEKEKAEF AKNREVLRIA EERLRIDDHL
DGYAMPDDYI TEKGKIDRKK KEEAMYKRYV DKDEYGQEKF VTEHEEWERE QASKAKAQIQ
SNERLDQGEY DYVLDEEQGI KWVMDSTQAG VGKGISKEEA FLAEQLKAAE KKALSMEETR
KSLPIYAYRE QFLAALAEYQ VLVIVGETGS GKTTQLPQYL HEAGYTKGGL KVGCTQPRRV
AAMSVAARVA DEMGVKVGNE VGYSIRFEDS TSDKTVLKYM TDGMLLREFM TEPDLGGYSA
LMIDEAHERT VHTDILLALV KDLARERPEM KLLISSATMD AKGFATYFDD APIFNIPGRR
YPVDIHYTPQ PEANYLAAAI TTVFQIHTSQ GKGDILVFLT GQDEIEAAEQ NITEISRKLG
SRVPELVICP IYANLPSELQ SKIFEPTPNG ARKVVLATNI AETSLTIDGI VYVIDPGFVK
ENNYNPATGM SKLVAVPCSR ASANQRSGRA GRVGPGKCFR LYTKWAFMNE MEDNTTPEIQ
RTNLNGVVLL LKSLGINDLL EFEFMNPPPT ETLIGALNQL FALQALNHQG ELTKLGRQMA
EFPTDPMLAK AILAADKLGC VEEVLSIVSM LSESAALFFR PKDKKIHADS ARARFTVKEG
GDHLTLLNIW NQWVDSDFSF VWAKENFLQQ RSLTRARDVR DQLAKLCERV EVTLSTVGQA
DLVPIQKAIT AGFFPNAARL QRGGDSYRTV KNNTTVYIHP SSVVMDNNPP VKMVIYYELV
QTTKEYMRSC LPIKPEWLHE AAPHFHKKKD LEALEDRKMP KARM
//
