ID S3DF36_GLAL2 Unreviewed; 356 AA.
AC S3DF36;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=phosphatidylserine decarboxylase {ECO:0000256|ARBA:ARBA00012243};
DE EC=4.1.1.65 {ECO:0000256|ARBA:ARBA00012243};
GN ORFNames=GLAREA_03563 {ECO:0000313|EMBL:EPE30596.1};
OS Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Helotiaceae; Glarea.
OX NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE30596.1, ECO:0000313|Proteomes:UP000016922};
RN [1] {ECO:0000313|EMBL:EPE30596.1, ECO:0000313|Proteomes:UP000016922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT the fungus Glarea lozoyensis.";
RL BMC Genomics 14:339-339(2013).
CC -!- COFACTOR:
CC Name=pyruvate; Xref=ChEBI:CHEBI:15361;
CC Evidence={ECO:0000256|ARBA:ARBA00001928};
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- PATHWAY: Phospholipid metabolism; phosphatidylethanolamine
CC biosynthesis. {ECO:0000256|ARBA:ARBA00024326}.
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DR EMBL; KE145363; EPE30596.1; -; Genomic_DNA.
DR RefSeq; XP_008082007.1; XM_008083816.1.
DR AlphaFoldDB; S3DF36; -.
DR STRING; 1116229.S3DF36; -.
DR GeneID; 19462618; -.
DR KEGG; glz:GLAREA_03563; -.
DR eggNOG; KOG2419; Eukaryota.
DR HOGENOM; CLU_029061_2_0_1; -.
DR OMA; KREWSIF; -.
DR OrthoDB; 1109500at2759; -.
DR UniPathway; UPA00558; -.
DR Proteomes; UP000016922; Unassembled WGS sequence.
DR GO; GO:0004609; F:phosphatidylserine decarboxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR003817; PS_Dcarbxylase.
DR InterPro; IPR033177; PSD-B.
DR NCBIfam; TIGR00163; PS_decarb; 1.
DR PANTHER; PTHR10067; PHOSPHATIDYLSERINE DECARBOXYLASE; 1.
DR PANTHER; PTHR10067:SF11; PHOSPHATIDYLSERINE DECARBOXYLASE; 1.
DR Pfam; PF02666; PS_Dcarbxylase; 1.
PE 4: Predicted;
KW Decarboxylase {ECO:0000256|ARBA:ARBA00022793};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Reference proteome {ECO:0000313|Proteomes:UP000016922};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..356
FT /note="phosphatidylserine decarboxylase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005374446"
FT REGION 330..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..356
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 356 AA; 40535 MW; FCF535FFF838780C CRC64;
MFGWLHAILD WILFHLKLIP NRQVGWKSLN RKTGQLEREQ EPVLKKLKLL ALFNPLTEWL
DTTHAMRLYI HNKSIKEGKE EAMPASHDRI KAFVEFYNIN MDDFEPSDLE KYRTFEDFFV
RRHKDGTRPI HEKNDPKKAI VCCDCRVVTY DTVPQAKKLW IKGTDFSITN LIMDVNLGAK
FDDGSVASFR LSPQDYHRYH SPVTGTIKEF KSLPGDYYEV DPIALRSRVN ILTSNARDYV
LIDTAEFGEV LFVAIGATDV GTVYIHEKYR TPGAEITKGD ELGIFQFGGS SIIVAFQKDR
IKFDDDLRDC SNACIQVSVE VGMSLGEATS SSHADVNGGD TISEEDHRSF ADVVKE
//
