ID   S3DH58_GLAL2            Unreviewed;      1243 AA.
AC   S3DH58;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};
GN   ORFNames=GLAREA_01820 {ECO:0000313|EMBL:EPE25908.1};
OS   Glarea lozoyensis (strain ATCC 20868 / MF5171).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Helotiaceae; Glarea.
OX   NCBI_TaxID=1116229 {ECO:0000313|EMBL:EPE25908.1, ECO:0000313|Proteomes:UP000016922};
RN   [1] {ECO:0000313|EMBL:EPE25908.1, ECO:0000313|Proteomes:UP000016922}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 20868 / MF5171 {ECO:0000313|Proteomes:UP000016922};
RX   PubMed=23688303; DOI=10.1186/1471-2164-14-339;
RA   Chen L., Yue Q., Zhang X., Xiang M., Wang C., Li S., Che Y.,
RA   Ortiz-Lopez F.J., Bills G.F., Liu X., An Z.;
RT   "Genomics-driven discovery of the pneumocandin biosynthetic gene cluster in
RT   the fungus Glarea lozoyensis.";
RL   BMC Genomics 14:339-339(2013).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PIRNR:PIRNR005719}.
CC   -!- SIMILARITY: Belongs to the SMC family. SMC1 subfamily.
CC       {ECO:0000256|ARBA:ARBA00005597}.
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DR   EMBL; KE145371; EPE25908.1; -; Genomic_DNA.
DR   RefSeq; XP_008087227.1; XM_008089036.1.
DR   AlphaFoldDB; S3DH58; -.
DR   STRING; 1116229.S3DH58; -.
DR   GeneID; 19460878; -.
DR   KEGG; glz:GLAREA_01820; -.
DR   eggNOG; KOG0018; Eukaryota.
DR   HOGENOM; CLU_001042_0_1_1; -.
DR   OMA; SYIRDHT; -.
DR   OrthoDB; 231904at2759; -.
DR   Proteomes; UP000016922; Unassembled WGS sequence.
DR   GO; GO:0008278; C:cohesin complex; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR   CDD; cd03275; ABC_SMC1_euk; 2.
DR   Gene3D; 1.10.287.1490; -; 2.
DR   Gene3D; 1.20.1060.20; -; 1.
DR   Gene3D; 3.30.70.1620; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003395; RecF/RecN/SMC_N.
DR   InterPro; IPR024704; SMC.
DR   InterPro; IPR028468; Smc1_ABC.
DR   InterPro; IPR010935; SMC_hinge.
DR   InterPro; IPR036277; SMC_hinge_sf.
DR   PANTHER; PTHR18937:SF12; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN; 1.
DR   PANTHER; PTHR18937; STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; 1.
DR   Pfam; PF06470; SMC_hinge; 1.
DR   Pfam; PF02463; SMC_N; 1.
DR   PIRSF; PIRSF005719; SMC; 1.
DR   SMART; SM00968; SMC_hinge; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF75553; Smc hinge domain; 1.
DR   SUPFAM; SSF57997; Tropomyosin; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00022776};
KW   Cell division {ECO:0000256|ARBA:ARBA00022618};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Hydrolase {ECO:0000313|EMBL:EPE25908.1};
KW   Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR005719};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016922}.
FT   DOMAIN          549..664
FT                   /note="SMC hinge"
FT                   /evidence="ECO:0000259|SMART:SM00968"
FT   REGION          78..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          995..1017
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          200..255
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          281..392
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          444..516
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          699..935
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1020..1081
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1243 AA;  142327 MW;  B823239A5AEA0243 CRC64;
     MGKLVRLELF NFKSYKGHHI LLFGDSYFTS IIGPNGSGKS NSMDAISFVL GIKSSHLRSA
     HLRDLVYRGR VLKTSKINDD GSAATPATNG HANGDAEGSD GESQSQKPAR NDPKSAWVMA
     VYEDDAGDEQ KWKRTITNQG ASEYRINDRI VTAQGYNEAL EAENILIKAR NFLVFQGDVE
     QIASQSPKDL TRLIEMVSGS LEHKAEYERL QEEAEQAAEN QNYNLHRRRG INSEIKQYQE
     QKKEAEAFQN KQDERDHAIV QHILWKLYHF QRVMDESSAS IGEHQENLKE FRRGVEKYEK
     QLEDARQAAL KVTKDVSKVE RNIKRKEKEI EEKENSLVPI DEKADYTNSQ IEKLRRRLTA
     LTKERDENHT KMQDLKKQLV TVEKAQKQFQ TQWEESLKKQ GRQLNEDDLK EYNILRSQVI
     TKTSSNQSQL DNLIRTMKTD EVTYNSLKGK VELHQSSVEK LQAEIKSIEE RKGATKSSVK
     EISGEIDTKK KEFNNIQSER VRVNQARTEL DEKLHEVLKT LHEATAGQRQ SDKETRTRET
     LVSLKRIFPG VKGRVGELCK PKQKKYDEAV ITALGRDFDS VVVETEKIGQ ECVQYLKDQR
     SPPMTFIPLD NIKVTAVESN LKNLSKARLT IDTIDFDSSL ERAFSYVCGS SIVCDDLPTA
     KEICHKRKIQ VKAVTLQGYI IHKAGSMTGG RGPEGGKKRK FEDQDVENLR KQQQKLQTQI
     EALPNVSRRG SAEETLQNDL NGLEQRLSYA KSELAAFEQN LASRRKELTH EKRQLAEMEP
     KYREKESELA SIREKVEEFQ SAVAKVEDSI FKKFCERLGY SDVRRYEAQQ GTLEQEAAEK
     KNEFEVQKKR LDQALSWETA RWREVDGRVK KMEAQISTWL QDIESYNAEK AELENAIDVD
     RAHQTEMEDE LQKQKEKLLS KNEKVNAARN ELHKRSKEID NRTKAITALE TELQRNSAGR
     YALLRRCRLE QITIPLTPES KKLDSLPVDE NLLQTDPDEM DVDEEEGTVE TAGPDDDDVE
     EQLQQKIADL NSELEKLNPN MRAVDRLDGV EARLKSTEKD FEDARKKAKQ SRDQFNEVKE
     KRFELFNKAF THISEQISHV YKDLTRSAAY PLGGQAYLDT EDGDSPYLSG IKYHAMPPLK
     RFRDMEHLSG GEKTMAALAL LFAVHSYQPS PFFVLDEVDA ALDNANVEKI KNYIREHAGP
     GMQFIVISLK TGLFQGSESL VGVFRDQEAN SSKTLTLDLR KYV
//