ID S3J135_9ENTR Unreviewed; 895 AA.
AC S3J135;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=HMPREF0201_01067 {ECO:0000313|EMBL:EPF18466.1};
OS Cedecea davisae DSM 4568.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Cedecea.
OX NCBI_TaxID=566551 {ECO:0000313|EMBL:EPF18466.1, ECO:0000313|Proteomes:UP000014585};
RN [1] {ECO:0000313|EMBL:EPF18466.1, ECO:0000313|Proteomes:UP000014585}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 4568 {ECO:0000313|EMBL:EPF18466.1,
RC ECO:0000313|Proteomes:UP000014585};
RA Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R., Courtney L.,
RA Fronick C., O'Laughlin M., Godfrey J., Wilson R.M., Miner T., Farmer C.,
RA Delehaunty K., Cordes M., Minx P., Tomlinson C., Chen J., Wollam A.,
RA Pepin K.H., Palsikar V.B., Zhang X., Suruliraj S., Perna N.T., Plunkett G.,
RA Warren W., Mitreva M., Mardis E.R., Wilson R.K.;
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPF18466.1}.
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DR EMBL; ATDT01000006; EPF18466.1; -; Genomic_DNA.
DR RefSeq; WP_016535392.1; NZ_KE161030.1.
DR AlphaFoldDB; S3J135; -.
DR STRING; 566551.HMPREF0201_01067; -.
DR PATRIC; fig|566551.4.peg.976; -.
DR HOGENOM; CLU_000445_113_0_6; -.
DR OrthoDB; 9806130at2; -.
DR Proteomes; UP000014585; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01987; USP_OKCHK; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF13492; GAF_3; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF02702; KdpD; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EPF18466.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 397..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 425..443
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 448..465
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 477..498
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 670..884
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 895 AA; 99259 MW; 1DF8437D00EEC993 CRC64;
MTEEPLRPNP DKLLEKVNRQ PRGKLKIFFG ACAGVGKTYA MLQEAQRLRA QGLDVLVGVV
ETHGRQETAE LLKGLSIQPP RRIHHRGRLV QEFDLDAALA RSPALILMDE LAHSNAPGSR
HPKRWQDVEE LLEAGIDVLT SVNVQHLESL NDVVGGVTGI QVRETVPDPI FDAADEVVLV
DLPPDDLRQR LHEGKVYISG QAERAIEHFF RKGNLIALRE LALRRTADRV DDQMRAWRDN
QGQEKVWHTR DAILLCIGHS AGNEKLVRTA ARLAAKLGSV WHAVYVETPQ LHRLPENQRR
SILGALRLAQ ELGAETATLA DPNEEKAVLR YAREHNLGKI IIGRHTTRRW WHRTSFADRL
AKRAPDLDLV IVALDEKPAP SPVRAPDMRS ISEKWRIQLR GCIVAVVLCA FITFIANQWL
VAFDAANLVM IYLLGVVIVA LFYGRWPSVL ATIVNVISFD LFFIAPRGTL AVSDVQYLLT
FGVMLTVGLV IGNLTAGVRY QARIARYREQ RTRHLYEMSK ALADDRTPQE VAATSVQFIN
NTFQARSLLL LPDEHGKLSR IAAEGEPAQW DEAIARWSFD KGQPAGAGTD TLPGVPYRIL
PLSTTERTLG LLVVEPENLR QLMIPEQQRL LETFTLLVAT ALDRLLLTAS EEQARLSSER
EQIRNSLLAA LSHDLRTPLT VLFGQAEILT LDLASEGSKH APQANEIRQH VLNTTRLVNN
LLDMARIQSG GFNLRKEWLT LEEVIGSALK MLEPGLGGRH IALNMPDPLM LIEVDGPLFE
RVLINLLENA AKYAGYKAEI GIKATAAAQK LDLEVWDSGP GIPAGKELLI FDKFARGNKE
SAIPGVGLGL AICRAIVEVH GGTIYALNRP EGGASFHVVL PLSPPPELPE MIEAL
//
