ID S3L6E9_TREMA Unreviewed; 480 AA.
AC S3L6E9;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Peptidase M20 dimerisation domain-containing protein {ECO:0000259|Pfam:PF07687};
GN ORFNames=HMPREF9194_00392 {ECO:0000313|EMBL:EPF32394.1};
OS Treponema maltophilum ATCC 51939.
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Treponemataceae;
OC Treponema.
OX NCBI_TaxID=1125699 {ECO:0000313|EMBL:EPF32394.1, ECO:0000313|Proteomes:UP000014541};
RN [1] {ECO:0000313|EMBL:EPF32394.1, ECO:0000313|Proteomes:UP000014541}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51939 {ECO:0000313|EMBL:EPF32394.1,
RC ECO:0000313|Proteomes:UP000014541};
RG The Broad Institute Genomics Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Leonetti C., Blanton J.M.,
RA Dewhirst F.E., Izard J., Walker B., Young S., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Treponema maltophilum ATCC 51939.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M20A family.
CC {ECO:0000256|ARBA:ARBA00006247}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPF32394.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ATFF01000002; EPF32394.1; -; Genomic_DNA.
DR RefSeq; WP_016524691.1; NZ_KE332518.1.
DR AlphaFoldDB; S3L6E9; -.
DR STRING; 1125699.HMPREF9194_00392; -.
DR PATRIC; fig|1125699.3.peg.394; -.
DR eggNOG; COG0624; Bacteria.
DR HOGENOM; CLU_021802_11_1_12; -.
DR OrthoDB; 9792335at2; -.
DR Proteomes; UP000014541; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.150.900; -; 1.
DR Gene3D; 3.30.70.360; -; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR036264; Bact_exopeptidase_dim_dom.
DR InterPro; IPR047177; Pept_M20A.
DR InterPro; IPR002933; Peptidase_M20.
DR InterPro; IPR011650; Peptidase_M20_dimer.
DR PANTHER; PTHR45962; N-FATTY-ACYL-AMINO ACID SYNTHASE/HYDROLASE PM20D1; 1.
DR PANTHER; PTHR45962:SF1; N-FATTY-ACYL-AMINO ACID SYNTHASE_HYDROLASE PM20D1; 1.
DR Pfam; PF07687; M20_dimer; 1.
DR Pfam; PF01546; Peptidase_M20; 1.
DR SUPFAM; SSF55031; Bacterial exopeptidase dimerisation domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000014541};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 234..380
FT /note="Peptidase M20 dimerisation"
FT /evidence="ECO:0000259|Pfam:PF07687"
SQ SEQUENCE 480 AA; 51899 MW; 5EB0474CE1F285B0 CRC64;
MNEKNPAEKK SAAAKSAKLA AVKSAKSAEA KSKLAAAVSA AERFASLIRC PTVSLPTDKD
TQQNDVQSDV FDRFHAELKK NYPAVFKACE RIKVGRYPLV LRWKGKDSSA SVVFAAHQDV
VPAAEHAERW KYEPFAGTIA EGAVWGRGAL DDKGSLCAIF EACESLAAEN FTPSCDIYLC
FSHNEETMGW GARAVADELE RRGVKPLFVL DEGGAVVEKP LPLMKGKAAM IGITEKGVAD
VRFCARSTGG HASTPPKQSP LGALGAFASS VEKKSPLKTH MTGALARMLS VLSRRMSFPL
NVLFRFPHFF APLIRAVFKA SGGAARALVQ TSCAFTMAQG SDAVNVLPAS AFLTANLRIS
GGDTLDSVMD SLQKRATKYG VRAELIRGHE ASPESVLNRG WDILCKALDA QFPGVSAVPY
IMLAASDARH YCKLCPAVYR FTPFEMTDAQ RGSVHGVDEH LEVANFERGV RFYRDVMQSI
//
