ID   S3W8E6_9LEPT            Unreviewed;       278 AA.
AC   S3W8E6;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Thioredoxin domain protein {ECO:0000313|EMBL:EPG76317.1};
GN   ORFNames=LEP1GSC058_1485 {ECO:0000313|EMBL:EPG76317.1};
OS   Leptospira fainei serovar Hurstbridge str. BUT 6.
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptospira.
OX   NCBI_TaxID=1193011 {ECO:0000313|EMBL:EPG76317.1, ECO:0000313|Proteomes:UP000014540};
RN   [1] {ECO:0000313|EMBL:EPG76317.1, ECO:0000313|Proteomes:UP000014540}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BUT 6 {ECO:0000313|EMBL:EPG76317.1,
RC   ECO:0000313|Proteomes:UP000014540};
RA   Harkins D.M., Durkin A.S., Selengut J.D., Sanka R., DePew J., Purushe J.,
RA   Ahmed A., van der Linden H., Goris M.G.A., Hartskeerl R.A., Vinetz J.M.,
RA   Sutton G.G., Nelson W.C., Fouts D.E.;
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EPG76317.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AKWZ02000001; EPG76317.1; -; Genomic_DNA.
DR   AlphaFoldDB; S3W8E6; -.
DR   STRING; 1193011.LEP1GSC058_1485; -.
DR   OrthoDB; 9811036at2; -.
DR   Proteomes; UP000014540; Unassembled WGS sequence.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR017937; Thioredoxin_CS.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR15337; ANTERIOR GRADIENT PROTEIN-RELATED; 1.
DR   PANTHER; PTHR15337:SF11; THIOREDOXIN DOMAIN CONTAINING PROTEIN HOMOLOG; 1.
DR   Pfam; PF13899; Thioredoxin_7; 1.
DR   Pfam; PF13174; TPR_6; 1.
DR   Pfam; PF13181; TPR_8; 1.
DR   SMART; SM00028; TPR; 3.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS00194; THIOREDOXIN_1; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
DR   PROSITE; PS50005; TPR; 3.
PE   4: Predicted;
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..278
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004513603"
FT   DOMAIN          14..136
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
FT   REPEAT          155..188
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          194..227
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          232..265
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   278 AA;  31743 MW;  ED2CFB1B6A7A922B CRC64;
     MNLRNPFLIL LFSVIFSVVS TDIAAVGVQW ESSVEKAFAK AKQEGKPIFI DVYADWCGYC
     KTLKKEIYPK KEVQAELSRF VLLSLDGDRF PNLKKKYQVS GYPTLLFLDR NGSITEKISG
     MPDAKMVVKT LRKAYSKRDQ EGDLLASLEK NPGDSKLLLK VGEYYFEARE YAKAANYFYK
     AFSSDEKRTT ENQHRALFNL GVTYSEMQNY EKTVKTFTLY LEKYPPGTGY AQAAFYYRGI
     AFKELGKKEE AKSDLTKALE LSSDPTEKKE LEGILRTL
//