ID S3XZT3_9MICO Unreviewed; 437 AA.
AC S3XZT3;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=PIN domain-containing protein {ECO:0000259|SMART:SM00670};
GN ORFNames=HMPREF1484_01182 {ECO:0000313|EMBL:EPH15546.1};
OS Dermabacter sp. HFH0086.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Dermabacteraceae;
OC Dermabacter.
OX NCBI_TaxID=1203568 {ECO:0000313|EMBL:EPH15546.1, ECO:0000313|Proteomes:UP000014577};
RN [1] {ECO:0000313|EMBL:EPH15546.1, ECO:0000313|Proteomes:UP000014577}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HFH0086 {ECO:0000313|EMBL:EPH15546.1,
RC ECO:0000313|Proteomes:UP000014577};
RG The Broad Institute Genomics Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Schmidt T.M., Dai D., Dover J.,
RA Walker B., Young S., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Allen A.W., Alvarado L., Arachchi H.M., Berlin A.M.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Dermabacter sp. HFH0086.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the PINc/VapC protein family.
CC {ECO:0000256|ARBA:ARBA00038093}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPH15546.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ATFO01000007; EPH15546.1; -; Genomic_DNA.
DR RefSeq; WP_016664092.1; NZ_KE340308.1.
DR AlphaFoldDB; S3XZT3; -.
DR STRING; 1203568.HMPREF1484_01182; -.
DR PATRIC; fig|1203568.3.peg.1158; -.
DR eggNOG; COG1875; Bacteria.
DR HOGENOM; CLU_022283_2_1_11; -.
DR Proteomes; UP000014577; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR CDD; cd09883; PIN_VapC_PhoHL-ATPase; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003714; PhoH.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR002716; PIN_dom.
DR PANTHER; PTHR30473:SF2; PIN DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR30473; PROTEIN PHOH; 1.
DR Pfam; PF02562; PhoH; 1.
DR Pfam; PF13638; PIN_4; 1.
DR SMART; SM00670; PINc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000014577};
KW Toxin-antitoxin system {ECO:0000256|ARBA:ARBA00022649}.
FT DOMAIN 5..132
FT /note="PIN"
FT /evidence="ECO:0000259|SMART:SM00670"
SQ SEQUENCE 437 AA; 47413 MW; D830296681DE8910 CRC64;
MNAPLTYVLD TSVVLADPHS IFRFAEHHVV LPIVVITELE GKRHHSELGY FARQSLRILD
DLREKHGTLA EPLPIGDQGG TVRVELNHQS PENLPDGFRL GDNDTRILSV AKNLQVEGAE
VTLVSKDLPM RIKASASGLK AEEYRAELAR DRAYTGITSA DITEEQMAAL WSDEGGARHT
GIEIPELADL GIHTGLKLTS PRGSALGRVL PNGNVRLVPG DGNVFGVTGR SAEQRIAIDL
LLDDELSIVS LGGRAGTGKS ALALCAGLEA VLEKRHQRKI MVFRPLYAVG GQELGYLPGD
HDDKMGPWAQ AVFDTLGSMV SGAVVDEVLG RGLLEVLPLT HIRGRSLHDA FVIVDEAQSL
ERNVLLTMLS RIGQNSRVVL THDVAQRDNL RVGRYDGVTS VIEALKGNEL FAHVTLQRSE
RSKVAELVTR VLDAPIA
//
