ID S4RDW7_PETMA Unreviewed; 1877 AA.
AC S4RDW7;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Programmed cell death 11 {ECO:0000313|Ensembl:ENSPMAP00000003399.1};
OS Petromyzon marinus (Sea lamprey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX NCBI_TaxID=7757 {ECO:0000313|Ensembl:ENSPMAP00000003399.1, ECO:0000313|Proteomes:UP000245300};
RN [1] {ECO:0000313|Ensembl:ENSPMAP00000003399.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
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DR STRING; 7757.ENSPMAP00000003399; -.
DR Ensembl; ENSPMAT00000003414.1; ENSPMAP00000003399.1; ENSPMAG00000003098.1.
DR GeneTree; ENSGT00390000012228; -.
DR HOGENOM; CLU_000845_1_1_1; -.
DR OMA; GQYLRAY; -.
DR Proteomes; UP000245300; Unplaced.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR CDD; cd05693; S1_Rrp5_repeat_hs1_sc1; 1.
DR CDD; cd05697; S1_Rrp5_repeat_hs5; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 8.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR045209; Rrp5.
DR InterPro; IPR048059; Rrp5_S1_rpt_hs1_sc1.
DR InterPro; IPR003029; S1_domain.
DR InterPro; IPR008847; Suf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR23270; PROGRAMMED CELL DEATH PROTEIN 11 PRE-RRNA PROCESSING PROTEIN RRP5; 1.
DR PANTHER; PTHR23270:SF10; PROTEIN RRP5 HOMOLOG; 1.
DR Pfam; PF00575; S1; 2.
DR Pfam; PF05843; Suf; 1.
DR SMART; SM00386; HAT; 5.
DR SMART; SM00316; S1; 13.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 8.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50126; S1; 11.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000245300};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 197..268
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 291..354
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 373..440
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 457..526
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 546..615
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 640..710
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 732..801
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 1043..1116
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 1155..1228
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 1236..1305
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 1334..1406
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT REPEAT 1731..1764
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1427..1525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1554..1590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1427..1444
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1452..1474
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1484..1523
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1566..1590
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1877 AA; 206286 MW; AF377C4BC5E0B3B5 CRC64;
CKAMEEDFPR GGVQPKERVA ARAIEKSAAH SDNLFGQQEL EIEGKKRRAK DVEGEKVKKL
KFEQEAISTK HAVLKPNKVQ FIDILKLKMV NPDMLVLGCV KVSLDHELEV GLPGCLTGNV
QIVHVCDAYT KSLGDNLDSN LESETVTPLS ELYPPGTLVP CRVMEVVQGK GNWCRINLSV
NPRDVNKDLS ASSLRPGMLL HGCVASVEDH GYMVDIGVYG TQAFLSKAKA QALVNSKKAG
QNLSVGQPVW CIVETVRSQG HSVQLSANPT KLSAAIANEK HGWTLDNLLP GVILSGTVER
VEHDGLVVEF LGLFEGSVDS LHLSPQVIYK KGQKVKVCVL HVMPSSKLIG LSTLPALLQP
GKPASDPIGF TVGDVFEDCA ISRILTGAGI LLVLPNGSPA FVHVKQISDK ERQFLSEDSK
HKCRVIAFSH VDQAAIASLR QSVIEGPFMR YSDLELGQTV EGTVLTVDKF GLQVRLTDYV
RGFVPLSHLA DVAVLHPEKK FSPGNEVTCK VLNCCAEKHK LMLTHKRALV RSKLRPLVSF
ESAVPGMVAH GTVVCVRDFG CIVRFYGNVK ALARRSDLGL DFGADPTQAF YTGQVVKAVV
LNSSPAEERM LVSLSGTMSG RETQDAGCPV QQTSFAIEVG KCVDVQVRCK SEKGLDVNVT
GSGAPGFMPM MHLSDNVHVC RLLLEVVEPG DVLSATCFSE RNGKILLTKK HALQVALSGG
NVAKTLDDLQ AGMLLVGVTR RMLPYGVSVE FPYALRGMAF KAALSDEYVV SCEEFYSVGQ
TVLAAVTRVD EEKSRLDISL RVSECLADAA LEGTALLSQA LRELVQARAL LASKGLGQIK
SREFPKPGQM LKATVEEVSA DRSVAFKSES APGVSLKATE HHVDGQQLSV GQEVSARVLF
VDFLASTVHV SLKAELLPKR KKKKQIQLRE GFVYFATVQF IGSDLAVASL EESSHLIFLP
LANHLNEMLR PNSGSLRVGE KLKVVVKCAD PEEHDGVLVA APDSGHLRNG AFRTRARTAS
VSEEGGEVTD GVYTVNGRAL RLGDVYKGTV KSSRGLRAMV TLPGGVMGRV HVSEIRDEAT
TGQKPTMSLK AGETVAVKVI GGQEIKTHKY LPITHQNLVI HLPELTMRPS KLNSNNKEDF
CIPSVKECLG SYQPGQTITC FVNKYQEERK ALWVDVNAVV SGRVEQLLIS NRPKVLDNPL
QKFRVGCAVQ ATVVACKVEQ ESLSLSLSGV YKLSPGTVTL GRVKCSQPGI GLLLSLPMGH
TGRVLLTDLN DSFVQKPLDA FEVGQIVPCY VLENGGKMRV MLSLRDSSTN PPTDEEEAEV
KDKELSSLED LTVGSVVRGY VHTIVNNQVL VNLSWCVMGR ISLRNLSKYF VSGSSLMERY
IRKGRLISVK VLSVDAETKR VELSSLPNDT GGKDLFPGSI GLRLWRSNDN KDETRKRKAA
ADTAEPVPEV KAVHPRSAKP RARGLKQCDL HGSFKREKKK KKRKTATEKA EECTDSGVEI
YFREGRDDSE TETKGKSAKA ERGAASLERL QAPGSFSWDA SLASLQTGIL GAHNGGGGID
TSDDEDDTDA AKKKQRKNRQ EAFAERKREE KELEQLEARL ADPSRVPQSV DDFDRLALSS
PNSSLVWLQY MAFHLQATEV DRARAVAERA LKTISFSREE QEKLNVWVAL LNLENLYGDE
ASLMRAFERA VQHNDALKAF RHLAQIYIGS DKFQQADVLY NKMLRRFRQE KAVWLAYGSF
LVQRGQTDSA RRLMQRALKS LPEREHVDVI VKFAQLDFRS GEVEHGVAVF ENTLSSYPKR
TDIWSIYIDM LAKHGTAQQI RAVFERVVHM NFSPKRMKFF FKRYLDYERK HGDAASVQRV
RQKALEYVEE KSSVGVK
//
