ID S4RKE3_PETMA Unreviewed; 354 AA.
AC S4RKE3;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Solute carrier organic anion transporter family member {ECO:0000256|RuleBase:RU362056};
OS Petromyzon marinus (Sea lamprey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX NCBI_TaxID=7757 {ECO:0000313|Ensembl:ENSPMAP00000005676.1, ECO:0000313|Proteomes:UP000245300};
RN [1] {ECO:0000313|Ensembl:ENSPMAP00000005676.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362056};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362056}.
CC -!- SIMILARITY: Belongs to the organo anion transporter (TC 2.A.60) family.
CC {ECO:0000256|RuleBase:RU362056}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362056}.
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DR AlphaFoldDB; S4RKE3; -.
DR STRING; 7757.ENSPMAP00000005676; -.
DR Ensembl; ENSPMAT00000005700.1; ENSPMAP00000005676.1; ENSPMAG00000005167.1.
DR GeneTree; ENSGT01080000257336; -.
DR OMA; RECEKEP; -.
DR Proteomes; UP000245300; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004156; OATP.
DR NCBIfam; TIGR00805; oat; 1.
DR PANTHER; PTHR11388; ORGANIC ANION TRANSPORTER; 1.
DR PANTHER; PTHR11388:SF99; SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1C1; 1.
DR Pfam; PF03137; OATP; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|RuleBase:RU362056};
KW Membrane {ECO:0000256|RuleBase:RU362056};
KW Reference proteome {ECO:0000313|Proteomes:UP000245300};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|RuleBase:RU362056};
KW Transmembrane helix {ECO:0000256|RuleBase:RU362056};
KW Transport {ECO:0000256|RuleBase:RU362056}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..354
FT /note="Solute carrier organic anion transporter family
FT member"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004532499"
FT TRANSMEM 43..64
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 71..92
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 181..210
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 231..254
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 311..333
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT REGION 116..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 354 AA; 38276 MW; 689BC8F73C7AB02D CRC64;
TLQVFLLCLS LLFFSKAMSG SYMKSSITSI ERHFDLPSSV AGIIDGGFEM GNLLVITAVS
YFGARFHRPR IIAAGATLMG LGTLLIALPH FLMGRYKYDY QSHLYGEGPQ WMCVPRGEQP
SLSQEPTSAE PASGSGCQHK AQSSLWVLIL VGNALRGIGE SPITPLGISF LDDHARADNS
AFYLGCVMTV GLIGPAVGFL VGSVCTKLFV DVGFVNMEEV TINPQDSRWV GAWWLGFLIA
GGITLLTALP LWFFPASVPH EEELATAAAV VATVVDGVDP AHHPSIRGRS PGSLFASVDF
LPSLRCLMAN PVYVCMLINY VMLMNAFMGF FTFKAKYLEE QFGETASRSN LIIG
//
