ID   S4RQ32_PETMA            Unreviewed;       624 AA.
AC   S4RQ32;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=Retinol saturase (all-trans-retinol 13,14-reductase) {ECO:0000313|Ensembl:ENSPMAP00000007318.1};
OS   Petromyzon marinus (Sea lamprey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC   Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX   NCBI_TaxID=7757 {ECO:0000313|Ensembl:ENSPMAP00000007318.1, ECO:0000313|Proteomes:UP000245300};
RN   [1] {ECO:0000313|Ensembl:ENSPMAP00000007318.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the carotenoid/retinoid oxidoreductase family.
CC       CrtISO subfamily. {ECO:0000256|ARBA:ARBA00005855}.
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DR   AlphaFoldDB; S4RQ32; -.
DR   STRING; 7757.ENSPMAP00000007318; -.
DR   Ensembl; ENSPMAT00000007350.1; ENSPMAP00000007318.1; ENSPMAG00000006612.1.
DR   GeneTree; ENSGT00390000017613; -.
DR   HOGENOM; CLU_019722_1_0_1; -.
DR   OMA; FCADVHY; -.
DR   Proteomes; UP000245300; Unplaced.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR002937; Amino_oxidase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR46091; BLR7054 PROTEIN; 1.
DR   PANTHER; PTHR46091:SF3; BLR7054 PROTEIN; 1.
DR   Pfam; PF01593; Amino_oxidase; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   3: Inferred from homology;
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245300}.
FT   DOMAIN          89..602
FT                   /note="Amine oxidase"
FT                   /evidence="ECO:0000259|Pfam:PF01593"
SQ   SEQUENCE   624 AA;  69375 MW;  AD9D18FB2E405D9F CRC64;
     MSLCVLCAWL LAPLALLALL VVLGVVLLAR HGVLPFGASA ENNPFKTDTR REPAALTVEK
     EAREKVIRQG FVENRVPKQL DAVVVGSGIG GLTTAALLAK AGRRVLVLEQ HTRAGGCCHT
     YQKKGFEFDV GIHYIGEMHN NSVSRTLIDQ LTDGQLQWVE LDNPFDTVVF GDPAAPRLVV
     PLYSGRRRFW DELHAAFPKD TKAIDKFHSL LQEVRKGLLY SPLLKLLPLW LSKLLIRSGI
     IDRLTSYFRL ASRSLSCVLA EITDNADLRA VMAYNFGDYG CPPKDTSFVM QAVLINHFVQ
     GSWYPVGGAS EIAMHIIPVI QRAGGAVLVR APVSRILLDS DGRACGVMVN KGGEEVQVNA
     PMVISDAGMF NTYEVLLSEE KLATAGAREQ LSRLQHGLGA FTVFVGLDGT KEQLKLKAAN
     VWLFKENDLD ASFSRFMALS KEEAAEADVP MLFISFPSAK DPCWEQRYPG KSTLAIVTFA
     PYEWFEEWKD EHVKKRGEEY MTFKMAMARR LLDSATDLFP QIRDNIEYIE AGSPLSHQHY
     IASPRGEIYG IHHNLPRFSA ETTAVLRPET SIPNLYLTGQ DVLTAGFTGA MFGGLLCAWR
     VLNRNIYWDL LSLRNKISPR KHSK
//