ID S4RXJ2_PETMA Unreviewed; 712 AA.
AC S4RXJ2;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Calponin-homology (CH) domain-containing protein {ECO:0000259|PROSITE:PS50021};
OS Petromyzon marinus (Sea lamprey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX NCBI_TaxID=7757 {ECO:0000313|Ensembl:ENSPMAP00000009933.1, ECO:0000313|Proteomes:UP000245300};
RN [1] {ECO:0000313|Ensembl:ENSPMAP00000009933.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the hook family.
CC {ECO:0000256|ARBA:ARBA00006946}.
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DR AlphaFoldDB; S4RXJ2; -.
DR STRING; 7757.ENSPMAP00000009933; -.
DR Ensembl; ENSPMAT00000009976.1; ENSPMAP00000009933.1; ENSPMAG00000009011.1.
DR GeneTree; ENSGT00940000167690; -.
DR HOGENOM; CLU_011214_1_0_1; -.
DR OMA; ELETENX; -.
DR Proteomes; UP000245300; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0031122; P:cytoplasmic microtubule organization; IEA:InterPro.
DR GO; GO:0030705; P:cytoskeleton-dependent intracellular transport; IEA:InterPro.
DR CDD; cd22222; HkD_Hook; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR008636; Hook_C.
DR InterPro; IPR043936; HOOK_N.
DR PANTHER; PTHR18947; HOOK PROTEINS; 1.
DR PANTHER; PTHR18947:SF39; PROTEIN HOOK; 1.
DR Pfam; PF05622; HOOK; 1.
DR Pfam; PF19047; HOOK_N; 1.
DR SUPFAM; SSF116907; Hook domain; 1.
DR PROSITE; PS50021; CH; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000245300}.
FT DOMAIN 1..124
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 557..595
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 692..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 169..384
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 576..595
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 712 AA; 80906 MW; 4A9533F574624D29 CRC64;
VRHANSIVSQ DIFALPQVTT FTENQQCLTV EDLADGVVLS DVLQKIDPGW FDAAWVTRVR
KDVGDSWRLK VSNLKKVLQG IQDYYSEVLG VQVSPACVPD VAAVGEHADH VEMGRLLQLV
LGCAINCENK QEHIENIMQL EESVQHVVMA AIQELLSREG MGPSVSMSAA DLEALENELK
RSTDALQETE AEKAEITQRC HVLDQQASAL LEERNALLAE NEALVERLHM LEAGEDCVDG
GPGSSSRRGL LHVQAQLEEL REENFRLEAA KDECRIQNEQ LHRELLDAQE KNVEMSSLVE
ETQILKDEMD ILRHSSSRVA QLEGTVESYR RRLEELGELR RQVRLLEERN EVSLTRALGL
EDELRRANAT RAQLEISRTQ LIEDKEKKSH EKKKSNYRTL LKNISWVSSI RQRLVLERDA
LREENDELHC SQLHSQADCY FLSFSASSMG PGDSLAGEIL PLDVQEQVAG LQSEKRALTR
RLEELERQQA DALSALATDS ACRHAQLEAD NRLQGEQVSA LQARVEELQS SLAEQVERAD
NATALNKKLN HQLETLQESR RKEPQEEQPQ QPPVPKTSER EEELESLLRK KTEDMRSMEE
RYKRYLEKAK LVIRTMDPKQ SPEMAALRGQ LLERERQLNQ LQKENEQILA QKQEEEKLMT
TAWYSMGMGL QRQSVQERLA AMGGTECSFL SRQRSVSRRT PQSFLANPAT PL
//
