ID   S4SPY0_CHLSB            Unreviewed;       216 AA.
AC   S4SPY0;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   SubName: Full=MHC class II DPA protein {ECO:0000313|EMBL:AFP92181.1};
DE   Flags: Fragment;
OS   Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Chlorocebus.
OX   NCBI_TaxID=60711 {ECO:0000313|EMBL:AFP92181.1};
RN   [1] {ECO:0000313|EMBL:AFP92181.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Blood {ECO:0000313|EMBL:AFP92181.1};
RX   PubMed=24676686; DOI=10.1007/s00251-014-0770-9;
RA   Aarnink A., Jacquelin B., Dauba A., Hebrard S., Moureaux E.,
RA   Muller-Trutwin M., Blancher A.;
RT   "MHC polymorphism in Caribbean African green monkeys.";
RL   Immunogenetics 66:353-360(2014).
CC   -!- SIMILARITY: Belongs to the MHC class II family.
CC       {ECO:0000256|RuleBase:RU004238}.
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DR   EMBL; KA650604; AFP92181.1; -; mRNA.
DR   AlphaFoldDB; S4SPY0; -.
DR   GO; GO:0042613; C:MHC class II protein complex; IEA:UniProtKB-KW.
DR   GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR   GO; GO:0002504; P:antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; IEA:UniProtKB-KW.
DR   CDD; cd05767; IgC1_MHC_II_alpha; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003006; Ig/MHC_CS.
DR   InterPro; IPR003597; Ig_C1-set.
DR   InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR   InterPro; IPR014745; MHC_II_a/b_N.
DR   InterPro; IPR001003; MHC_II_a_N.
DR   PANTHER; PTHR19944:SF64; HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DP ALPHA 1 CHAIN; 1.
DR   PANTHER; PTHR19944; MHC CLASS II-RELATED; 1.
DR   Pfam; PF07654; C1-set; 1.
DR   Pfam; PF00993; MHC_II_alpha; 1.
DR   SMART; SM00407; IGc1; 1.
DR   SMART; SM00920; MHC_II_alpha; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   SUPFAM; SSF54452; MHC antigen-recognition domain; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
DR   PROSITE; PS00290; IG_MHC; 1.
PE   2: Evidence at transcript level;
KW   Adaptive immunity {ECO:0000256|ARBA:ARBA00023130};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Immunity {ECO:0000256|ARBA:ARBA00022859};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   MHC II {ECO:0000256|ARBA:ARBA00023182};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..31
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           32..216
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004532895"
FT   DOMAIN          118..198
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   NON_TER         216
FT                   /evidence="ECO:0000313|EMBL:AFP92181.1"
SQ   SEQUENCE   216 AA;  24860 MW;  1A6874E1F8059FF0 CRC64;
     MRPEDRMFQT RAVILSTLSL AFLLSLRGAG AIKADHVSTY AMFVQTHRPT GEYMFEFDED
     EMFYVDLDKK ETVWHLEEFG RALSFEAQGG LANIAILNNN LNITIQRSNY TQAANDPPEV
     TVFPKEPVEL GQPNTLICHI DKFFPPVLNV TWLCNGQPVT EGVAESLFLP RTDYSFHKFH
     YLTFVPSAED YYDCRVEHWG LDQPLLKHWE AQEPIQ
//