ID S4XEJ1_9CORY Unreviewed; 492 AA.
AC S4XEJ1;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000256|HAMAP-Rule:MF_00212};
DE EC=1.1.5.4 {ECO:0000256|HAMAP-Rule:MF_00212};
DE AltName: Full=MQO {ECO:0000256|HAMAP-Rule:MF_00212};
DE AltName: Full=Malate dehydrogenase [quinone] {ECO:0000256|HAMAP-Rule:MF_00212};
GN Name=mqo {ECO:0000256|HAMAP-Rule:MF_00212};
GN ORFNames=A606_06635 {ECO:0000313|EMBL:AGP30974.1};
OS Corynebacterium terpenotabidum Y-11.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=1200352 {ECO:0000313|EMBL:AGP30974.1, ECO:0000313|Proteomes:UP000014809};
RN [1] {ECO:0000313|EMBL:AGP30974.1, ECO:0000313|Proteomes:UP000014809}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Y-11 {ECO:0000313|EMBL:AGP30974.1,
RC ECO:0000313|Proteomes:UP000014809};
RA Ruckert C., Albersmeier A., Al-Dilaimi A., Szczepanowski R., Kalinowski J.;
RT "Complete genome sequence of Corynebacterium terpenotabidum Y-11 (=DSM
RT 44721).";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001139, ECO:0000256|HAMAP-
CC Rule:MF_00212};
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|HAMAP-Rule:MF_00212};
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC oxaloacetate from (S)-malate (quinone route): step 1/1.
CC {ECO:0000256|ARBA:ARBA00005012, ECO:0000256|HAMAP-Rule:MF_00212}.
CC -!- SIMILARITY: Belongs to the MQO family. {ECO:0000256|HAMAP-
CC Rule:MF_00212}.
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DR EMBL; CP003696; AGP30974.1; -; Genomic_DNA.
DR AlphaFoldDB; S4XEJ1; -.
DR STRING; 1200352.A606_06635; -.
DR KEGG; cter:A606_06635; -.
DR PATRIC; fig|1200352.3.peg.1352; -.
DR eggNOG; COG0579; Bacteria.
DR HOGENOM; CLU_028151_0_0_11; -.
DR OrthoDB; 9763983at2; -.
DR UniPathway; UPA00223; UER01008.
DR Proteomes; UP000014809; Chromosome.
DR GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR HAMAP; MF_00212; MQO; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR006231; MQO.
DR NCBIfam; TIGR01320; mal_quin_oxido; 1.
DR PANTHER; PTHR43104; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43104:SF2; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF06039; Mqo; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|HAMAP-Rule:MF_00212};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630, ECO:0000256|HAMAP-
KW Rule:MF_00212};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002, ECO:0000256|HAMAP-
KW Rule:MF_00212}; Reference proteome {ECO:0000313|Proteomes:UP000014809};
KW Tricarboxylic acid cycle {ECO:0000256|HAMAP-Rule:MF_00212}.
SQ SEQUENCE 492 AA; 53584 MW; 2A1B2A474957D4B2 CRC64;
MSPAKNDHVD VALVGAGVIS TTLSVMLREL QPDWTQLIIE RQDIPASESS DPWNNAGTGH
SALCELNYTP EVNGKIDTTK AVNINEKFQV SRQFWSYLVE NGTLGDPSEW INATPHMSFG
HGEKQSAYIK ARYEALKDNP LFPDMHLTTD PEEFTAKVPL MGKGRDFSEQ VALSWIDAGT
DINYGALTRQ YLDAVTAQGV EVRYGSQVTN VTREGSGWKL TVKNLHNGDT TTVHAKFVFI
GAGGMALPLL QKAGIPEIKG FAGFPVSGQW LRCTNQELVD QHAAKVYGQA AVGAPPMSVP
HLDTRVIDGK KGLLFGPYAG WTPKFLKQGS NLDLFKSLRP GNIPSYLGVA VKELGLTKYL
VTEVLKNQAA RVESLREYMP DARDEDWELV TAGQRVQVIK PAKAPTFGTL EFGTALINSA
DGSIAGLMGA SPGASIAPSA MLEVLQACFS DRIDAWTPKL KDMIPSFGGK LSEDLALYNQ
QWDRSQKSLK LA
//
