ID S4XW85_SORCE Unreviewed; 734 AA.
AC S4XW85;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Leucine-binding protein domain-containing protein {ECO:0000259|Pfam:PF13458};
GN ORFNames=SCE1572_20250 {ECO:0000313|EMBL:AGP36621.1};
OS Sorangium cellulosum So0157-2.
OC Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae; Sorangium.
OX NCBI_TaxID=1254432 {ECO:0000313|EMBL:AGP36621.1, ECO:0000313|Proteomes:UP000014803};
RN [1] {ECO:0000313|EMBL:AGP36621.1, ECO:0000313|Proteomes:UP000014803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=So0157-2 {ECO:0000313|EMBL:AGP36621.1,
RC ECO:0000313|Proteomes:UP000014803};
RX PubMed=23812535; DOI=10.1038/srep02101;
RA Han K., Li Z.F., Peng R., Zhu L.P., Zhou T., Wang L.G., Li S.G.,
RA Zhang X.B., Hu W., Wu Z.H., Qin N., Li Y.Z.;
RT "Extraordinary expansion of a Sorangium cellulosum genome from an alkaline
RT milieu.";
RL Sci. Rep. 3:2101-2101(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. LivHM subfamily. {ECO:0000256|ARBA:ARBA00037998}.
CC -!- SIMILARITY: Belongs to the leucine-binding protein family.
CC {ECO:0000256|ARBA:ARBA00010062}.
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DR EMBL; CP003969; AGP36621.1; -; Genomic_DNA.
DR AlphaFoldDB; S4XW85; -.
DR STRING; 1254432.SCE1572_20250; -.
DR KEGG; scu:SCE1572_20250; -.
DR PATRIC; fig|1254432.3.peg.4572; -.
DR eggNOG; COG0559; Bacteria.
DR eggNOG; COG0683; Bacteria.
DR HOGENOM; CLU_377615_0_0_7; -.
DR OrthoDB; 9791590at2; -.
DR Proteomes; UP000014803; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR CDD; cd06338; PBP1_ABC_ligand_binding-like; 1.
DR CDD; cd06582; TM_PBP1_LivH_like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR InterPro; IPR001851; ABC_transp_permease.
DR InterPro; IPR028081; Leu-bd.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR11795:SF445; AMINO ACID ABC TRANSPORTER PERMEASE PROTEIN; 1.
DR PANTHER; PTHR11795; BRANCHED-CHAIN AMINO ACID TRANSPORT SYSTEM PERMEASE PROTEIN LIVH; 1.
DR Pfam; PF02653; BPD_transp_2; 1.
DR Pfam; PF13458; Peripla_BP_6; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
PE 3: Inferred from homology;
KW Amino-acid transport {ECO:0000256|ARBA:ARBA00022970};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 459..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 487..505
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 511..530
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 542..563
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 583..606
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 635..660
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 672..697
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 704..724
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 58..417
FT /note="Leucine-binding protein"
FT /evidence="ECO:0000259|Pfam:PF13458"
SQ SEQUENCE 734 AA; 77752 MW; F5A829591E5A7CBE CRC64;
MVCAHVGAEV YDAAMRRLVL FFLTLVAIAW SAPSPARAQP SALDRQGTSA APSRTAIVGF
TASLTGNVNV ESTRQTNGIK MWVDDVNKAG GIRLADGSAV AVDIRFYDDE SNKDRVQQLY
TRLINEDRAD FLISPYSSGL TDAAAVIAEQ YGRVMVTAGA SSDSTHDKGY SLAFMTYTPA
SRYLTGAFDL LAHLDPSAKR VAIVHERDKF STDVATAAKS HGEAKGYEIV LFEGYASGTT
DFAPFINRMP GDVDAIMGGG HFADTSTFAR QLAEKGVHAK FVALLVAPPE PRFGELGAAA
LGVIGPSQWE STVKYSPEAA RAAGLPWHGP SVDDFVARYR ARFGDTPSYH GAGGYAAGLV
LEQAIARAGS LETAKVKAAL DGTDMLTFFG HTKYDTSAKR HGRQVGHEMV YIQWQKDEQG
RLVKRVVWPE DASTAKPLVP ARDQAAAGPS QLLTSLVDGL MLGFVYGLAA MGMTLIWGIL
RIINLSHGAV IALGMFASYF LFTHLGVNPY VGLVAVAGAG LLLGLLIYPV AVHRVIHAPH
HLTTLLATFA VNMIFIGLGT ALLTTTPRNI DYSLGTARLG PVALPGTRLM AALMAILVAS
ALTLFLRRTR LGKAIRAVAS NRASAELMGI PSSRVLALSF GLGTMLAAAS GGLIATFFPF
TILSGESYQL KSFVIGVLGG LGNPIGALAG GLLLGMLEGL IPMFLPVSWV PVVEFALFVL
VLLLRPSGLL GART
//
