ID S4Y0V8_SORCE Unreviewed; 1775 AA.
AC S4Y0V8;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 62.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=SCE1572_19755 {ECO:0000313|EMBL:AGP36533.1};
OS Sorangium cellulosum So0157-2.
OC Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae; Sorangium.
OX NCBI_TaxID=1254432 {ECO:0000313|EMBL:AGP36533.1, ECO:0000313|Proteomes:UP000014803};
RN [1] {ECO:0000313|EMBL:AGP36533.1, ECO:0000313|Proteomes:UP000014803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=So0157-2 {ECO:0000313|EMBL:AGP36533.1,
RC ECO:0000313|Proteomes:UP000014803};
RX PubMed=23812535; DOI=10.1038/srep02101;
RA Han K., Li Z.F., Peng R., Zhu L.P., Zhou T., Wang L.G., Li S.G.,
RA Zhang X.B., Hu W., Wu Z.H., Qin N., Li Y.Z.;
RT "Extraordinary expansion of a Sorangium cellulosum genome from an alkaline
RT milieu.";
RL Sci. Rep. 3:2101-2101(2013).
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
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DR EMBL; CP003969; AGP36533.1; -; Genomic_DNA.
DR STRING; 1254432.SCE1572_19755; -.
DR KEGG; scu:SCE1572_19755; -.
DR PATRIC; fig|1254432.3.peg.4469; -.
DR eggNOG; COG0318; Bacteria.
DR eggNOG; COG1020; Bacteria.
DR HOGENOM; CLU_000022_0_9_7; -.
DR Proteomes; UP000014803; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:InterPro.
DR CDD; cd12114; A_NRPS_TlmIV_like; 1.
DR CDD; cd05931; FAAL; 1.
DR CDD; cd19531; LCL_NRPS-like; 1.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR040097; FAAL/FAAC.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 2.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF00668; Condensation; 1.
DR Pfam; PF00550; PP-binding; 2.
DR SMART; SM00823; PKS_PP; 2.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00455; AMP_BINDING; 2.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 590..665
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1667..1742
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 1737..1775
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1749..1775
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1775 AA; 189679 MW; 83516DA106CF1489 CRC64;
MDSGAAFETL VELGRGRAAR LGDELAYSFL VDGESERLDV TFAEIDRRAR AVGAALQAIA
AAGERAVLLY APGLDYVAAF LGCLYAGVVA VPAYPPDPAR LGRTLPRLEA IAADAGARVV
LTTEAIAAMG DALAEQAPAL RAGRWVSTDA LAPGVEEAWR PPAISRGTLA LLQYTSGSTG
APKGVMLTHG NLLANLGAIA RGFRTGRASR GVIWLPPFHD MGLIGGVLEP LYAAFPVALM
SPLAFLERPM RWLRAVARFG ATVSGGPNFA YDLCARKATA ADVAALDLST WDVAFTGAEP
VRHETLERFA ATFAPCGFRR EAFYPCYGLA EGTLIVTGGE RGAGPALVTV DREALAGGRA
APPAPGRAAQ TLVACGRAVD AGGEVRIVDP ASTRDREDGE VGEIWVRGPS VSRGYWGRAE
ATAEAFGARR EGAPDEGPYL RTGDLGYLRD GALFVTGRLK DLILVRGRNL YPDDLERTAE
ASHPALRRGC CAAFGVEAEG EERLVLVQEV DPRGAPDLAE VVAAVRREVQ LQHDVAAHAV
VLIARGTIPK TSSGKIQRGA CRAAFLAGDL EELARGSLDA GAPEGHAIEA PSTDLEREVA
AIWREVLGAP RLGATDGFFE LGGDSLAAMQ VIGRLRARLG LRVELSALFE APTVRALSRR
LEAAARPAMA LGALGGGEGA EGPGPIPRAP DAADHPLSYE QERLWILDQL LPGLTAYNLA
PAARLRGPLD REALARALEG LISRHAALRA TFAASPDPVQ RIGERRDVPV RFVDVSDQPE
GERERAARLA ARAELTTPFD LAAGPLLRAR LVRLGPEEHV LVLGVHHIAI DGWSFAPLLR
DLGALYESCR RGGAPALPPL AAQYVDFARW QRQALSGARL EGLVAWWARR LCDLPTVELP
TDRPRGAVQT FAGAERTAAL PRRLLGELDA LCQRAEVTRF MAWLAVLAVA LRRATGQDDL
AIGTAVANRP RPELEGLVGM FVNTLVLRVD LAGDPSFAEL LRRARATALE AFEHQDAPFE
KVVEALQPRR DMSRSPLFQV MLVVQSAPMP AMALGGLEVE LLDLGVETTR FDLRFSVEAR
GGEEVVSLQY NTDLFDPQTA DELLESLVQI AERAVRAPEA RVAALLLTPE ERRRALVTWN
ATEAPYEDHL CLHEPFFARA SEQPEAVAVV AGGRRLTYAE LRRRALAVSA RVRRAGQGRG
QLVAIAMDKG WEQVAAALGV LHAGAAYLPI DPALPRERLA HLLAHGEARL ALTQSHVDAR
IDWPAGVERA LVDELDELGE LDGDLRLPQR AAPAPGDLAY VIYTSGSTGQ PKGVMIDHRG
AVNTILDVNR RFGVGRDDRV LALSSLSFDL SVYDLFGTLA AGGAIVLPPP GPGPQPDAWA
ALVRAERVTV WNSVPALLQL ALDAAPAGAS TMAPPDLASL RLVLLSGDWI DLKLPERIRA
ASPSARIVSL GGATEASIWS ILHPIDRVDP RWRSVPYGRP MANQRVYVLD QALEPCPIGV
PGELYIGGVG VALGYFRDEA RTAASFVTHP ATGERLYRTG DLARYFRDGA VELLGRVDFQ
VKVRGYRVEL GEIEAALLRH PDVKEAAVAV KQDPSGDRRL VAYVIGAGGL DPQGILASAR
RALPEYMVPS ACVPVDAFPL SANGKVDRAA LAAIDPRGGH GEAPRIPPRT PTERAIVGAL
KEVLQVEQIG VNENLFEIGL TSLLAVRAQR LLKERLRAPV AVADLFQSPT IEALAARVDA
SDPARGSTDA AEQRADARRD AARRRQAARG DRSNG
//
