ID S4YAM8_SORCE Unreviewed; 446 AA.
AC S4YAM8;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Cobalamin biosynthesis protein CobW {ECO:0000313|EMBL:AGP41361.1};
GN ORFNames=SCE1572_46865 {ECO:0000313|EMBL:AGP41361.1};
OS Sorangium cellulosum So0157-2.
OC Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae; Sorangium.
OX NCBI_TaxID=1254432 {ECO:0000313|EMBL:AGP41361.1, ECO:0000313|Proteomes:UP000014803};
RN [1] {ECO:0000313|EMBL:AGP41361.1, ECO:0000313|Proteomes:UP000014803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=So0157-2 {ECO:0000313|EMBL:AGP41361.1,
RC ECO:0000313|Proteomes:UP000014803};
RX PubMed=23812535; DOI=10.1038/srep02101;
RA Han K., Li Z.F., Peng R., Zhu L.P., Zhou T., Wang L.G., Li S.G.,
RA Zhang X.B., Hu W., Wu Z.H., Qin N., Li Y.Z.;
RT "Extraordinary expansion of a Sorangium cellulosum genome from an alkaline
RT milieu.";
RL Sci. Rep. 3:2101-2101(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR EMBL; CP003969; AGP41361.1; -; Genomic_DNA.
DR RefSeq; WP_020741211.1; NC_021658.1.
DR AlphaFoldDB; S4YAM8; -.
DR STRING; 1254432.SCE1572_46865; -.
DR KEGG; scu:SCE1572_46865; -.
DR PATRIC; fig|1254432.3.peg.10598; -.
DR eggNOG; COG0523; Bacteria.
DR HOGENOM; CLU_017452_0_0_7; -.
DR OrthoDB; 9808822at2; -.
DR Proteomes; UP000014803; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 352..445
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
SQ SEQUENCE 446 AA; 49116 MW; A4E9BD6C0FB609AF CRC64;
MNPGKIPVTV LTGFLGAGKT TLLNRILTEN HGKRIAVIEN EFGEIGIDQA LVINADEEVF
EMNNGCICCT VRGDLIRILG SLMKRKDRFD HVLVETTGLA DPGPVAQTFF VDDDVRELFA
LDAIVTLVDA KHIHLHLEDS SECKEQIAFA DVIVLNKADL VAGGDLDALE RRLRGMNALA
RVLRATGADV PIADVLGVGG FDLDRALAQR PAFLDPEYPF EWAGAFDLEE GDCDLALEPG
PDETMDVVVL PLAPSEDPGA REAAERAVRA WAEPAARVVP GDRLEIGARP SRLDLRAQGT
MRFRLTAPKR GRYGLYLQHL PGEFGARLES GGVVEPAGSR EFAAGHSHDE QVSSVGIHLE
GALDRERLNR WVSELLREKG TDIFRMKGIL NLRGSDSRFV FQGVHMLFDG REDRPWGSER
RASDLVFIGR NLDREQLTRG FRRCLA
//
