ID S5XJ92_PARAH Unreviewed; 806 AA.
AC S5XJ92;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=GAF sensor protein {ECO:0000313|EMBL:AGT07254.1};
GN ORFNames=JCM7686_0143 {ECO:0000313|EMBL:AGT07254.1};
OS Paracoccus aminophilus JCM 7686.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Paracoccus.
OX NCBI_TaxID=1367847 {ECO:0000313|EMBL:AGT07254.1, ECO:0000313|Proteomes:UP000015480};
RN [1] {ECO:0000313|EMBL:AGT07254.1, ECO:0000313|Proteomes:UP000015480}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 7686 {ECO:0000313|EMBL:AGT07254.1};
RX PubMed=24517536; DOI=10.1186/1471-2164-15-124;
RA Dziewit L., Czarnecki J., Wibberg D., Radlinska M., Mrozek P., Szymczak M.,
RA Schluter A., Puhler A., Bartosik D.;
RT "Architecture and functions of a multipartite genome of the methylotrophic
RT bacterium Paracoccus aminophilus JCM 7686, containing primary and secondary
RT chromids.";
RL BMC Genomics 15:124-124(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC family. {ECO:0000256|ARBA:ARBA00009773}.
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DR EMBL; CP006650; AGT07254.1; -; Genomic_DNA.
DR AlphaFoldDB; S5XJ92; -.
DR STRING; 1367847.JCM7686_0143; -.
DR KEGG; pami:JCM7686_0143; -.
DR PATRIC; fig|1367847.3.peg.81; -.
DR eggNOG; COG0628; Bacteria.
DR eggNOG; COG2203; Bacteria.
DR HOGENOM; CLU_021513_0_0_5; -.
DR Proteomes; UP000015480; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 3.30.450.40; -; 1.
DR InterPro; IPR002549; AI-2E-like.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR PANTHER; PTHR43102:SF2; GAF DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43102; SLR1143 PROTEIN; 1.
DR Pfam; PF01594; AI-2E_transport; 1.
DR Pfam; PF01590; GAF; 1.
DR SMART; SM00065; GAF; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000015480};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 62..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 640..782
FT /note="GAF"
FT /evidence="ECO:0000259|SMART:SM00065"
FT REGION 782..806
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 806 AA; 87264 MW; 3732EF3CBC22D4D0 CRC64;
MHRAVGLHTP SLLRAAMTQD PRSDGQVPTF RSDQTDVVKL AAALVIVTIL IGTLYVGKGV
LIPLAIAFLI SFVLSPLVNW LARRGLSRLL AVGLVMLTVG IVIAGIGTLV GSQVRTLSAQ
LPTYQTTIRT KIDSLAQQMR GPGVFDGALE TVNTVQKEVT QAVQGSPETA GVSKVEVVPA
ATSPFQTAKD WLIPALSPLA TAGIVLVFVF LVLLDSGDLR DRLLRLMGGN LHRSTDALDE
AGTRISKYLL MQIIVNVTYA LPLGLGLWYL GVPGWLLWAV FAAFMRFIPY IGSMLSAIFP
IGLAFAVDPG WDMVIWTTIL IVFLELVSGN IIEPLLYGTT TGLSAISLIA AATFWTALWG
PVGLVLSTPL TVCLLVVGRY LPQLQFLETL LGSAPVLDVP TRIYQRLLAD DPDDALTIVE
DTIEDGDVAG FYSDTGIAVL RQASDDFLGN ARAEHRLRVA NGMDLLLEDL RADYPPPAAG
QTRPRIACIG GKWEVDSIAC EMLSHALSLE GLPATERREG ALTSRYVDKL DLDGIEIICL
SYFSRDPESS IRSFCRRLRQ RWPGRKIVLA LWNAPETLLD PDQIRALGAD EVVASVDEAV
RRIARMISPE IAEQALIADA PENDAARVEA LLETDILDGH ARDELDALAK RAADVFNVRF
AVISAIDADR EFIVGQSMEL PGELTRDGTE MIVMPRDDAI CDHVVASGET LVVNDTERDP
HFAEHPAIRL WHTRFYAGAP LTTNKGHVLG ALCLLDTEPR KLDDEEIELL GTMAADIVAV
MTGEEGEVPE PKPEPGSASL GQAVPD
//
