ID S6D7C1_9EURY Unreviewed; 492 AA.
AC S6D7C1;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE SubName: Full=Glutamate synthase NADH-NADPH small subunit subfamily protein {ECO:0000313|EMBL:ERJ05577.1};
DE EC=1.4.1.13 {ECO:0000313|EMBL:CCQ32506.1, ECO:0000313|EMBL:ERJ05577.1};
DE SubName: Full=Glutamate synthase [NADPH] small chain {ECO:0000313|EMBL:CCQ32506.1};
GN Name=gltD {ECO:0000313|EMBL:ERJ05577.1};
GN ORFNames=HLRTI_002459 {ECO:0000313|EMBL:ERJ05577.1}, HTIA_0358
GN {ECO:0000313|EMBL:CCQ32506.1};
OS Halorhabdus tiamatea SARL4B.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Halorhabdus.
OX NCBI_TaxID=1033806 {ECO:0000313|EMBL:CCQ32506.1, ECO:0000313|Proteomes:UP000015381};
RN [1] {ECO:0000313|EMBL:ERJ05577.1, ECO:0000313|Proteomes:UP000003861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SARL4B {ECO:0000313|EMBL:ERJ05577.1,
RC ECO:0000313|Proteomes:UP000003861};
RX PubMed=21705593; DOI=10.1128/JB.05462-11;
RA Antunes A., Alam I., Bajic V.B., Stingl U.;
RT "Genome sequence of Halorhabdus tiamatea, the first archaeon isolated from
RT a deep-sea anoxic brine lake.";
RL J. Bacteriol. 193:4553-4554(2011).
RN [2] {ECO:0000313|EMBL:ERJ05577.1, ECO:0000313|Proteomes:UP000003861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SARL4B {ECO:0000313|EMBL:ERJ05577.1,
RC ECO:0000313|Proteomes:UP000003861};
RX PubMed=24324765;
RA Alam I., Antunes A., Kamau A.A., Ba Alawi W., Kalkatawi M., Stingl U.,
RA Bajic V.B.;
RT "INDIGO - INtegrated Data Warehouse of MIcrobial GenOmes with Examples from
RT the Red Sea Extremophiles.";
RL PLoS ONE 8:E82210-E82210(2013).
RN [3] {ECO:0000313|EMBL:CCQ32506.1, ECO:0000313|Proteomes:UP000015381}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SARL4B {ECO:0000313|Proteomes:UP000015381}, and Type strain:
RC SARL4B {ECO:0000313|EMBL:CCQ32506.1};
RX PubMed=24428220; DOI=10.1111/1462-2920.12393;
RA Werner J., Ferrer M., Michel G., Mann A.J., Huang S., Juarez S.,
RA Ciordia S., Albar J.P., Alcaide M., La Cono V., Yakimov M.M., Antunes A.,
RA Taborda M., Da Costa M.S., Amann R.I., Gloeckner F.O., Golyshina O.V.,
RA Golyshin P.N., Teeling H.;
RT "Halorhabdus tiamatea: proteogenomics and glycosidase activity measurements
RT identify the first cultivated euryarchaeon from a deep-sea anoxic brine
RT lake as potential polysaccharide degrader.";
RL Environ. Microbiol. 16:2525-2537(2014).
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; HF571520; CCQ32506.1; -; Genomic_DNA.
DR EMBL; AFNT02000030; ERJ05577.1; -; Genomic_DNA.
DR RefSeq; WP_020935953.1; NZ_AFNT02000030.1.
DR STRING; 1033806.HTIA_0358; -.
DR GeneID; 23798298; -.
DR KEGG; hti:HTIA_0358; -.
DR PATRIC; fig|1033806.12.peg.356; -.
DR eggNOG; arCOG01292; Archaea.
DR HOGENOM; CLU_000422_3_1_2; -.
DR OrthoDB; 27922at2157; -.
DR Proteomes; UP000003861; Unassembled WGS sequence.
DR Proteomes; UP000015381; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004355; F:glutamate synthase (NADPH) activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0006537; P:glutamate biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR006005; Glut_synth_ssu1.
DR InterPro; IPR009051; Helical_ferredxn.
DR NCBIfam; TIGR01317; GOGAT_sm_gam; 1.
DR PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00419; ADXRDTASE.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 2.
DR PROSITE; PS51379; 4FE4S_FER_2; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Glutamate biosynthesis {ECO:0000256|ARBA:ARBA00023164};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:CCQ32506.1}.
FT DOMAIN 39..71
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 492 AA; 54299 MW; 067C1835700D2A5E CRC64;
MTERHPGGYR RHRRRPIGKR DPDERKDDYD EVWAEKWDDE HLAEQGERCM DCGTPTCMGG
CPIGNIIPDW NDLVHRGDWK RALERLHATN NFPEFTGYNC PAPCENSCVL AYNDDPVTIK
SIERAIADRG WEEGWIQPEP PEERTDYEVA IVGSGPAGLS AAQQLNRAGH HVTVFERNDE
VGGLMRYGIP DQKFAKHRVE RRVDQLREEG ITFETNAEIG GNVPVERIEE DFDASVIAVG
SQKPIDLPLP GRDLDGIHFA MDYLTQQNRR NARKDVPGPD IDAEGKNVVV LGGGDTGADC
VATAHRQGAD QVVQIELLPK PPVERPPGNP WPDQPQTYKK TYAQEEGAIE EYNVDTNAFV
DTDGDGVVDT LEADRVIWED GGEGPPEKKV SESNLEIPAD LVILAIGFEA PESSPFEPLG
VEVEDDGTLV TDDRMMTSAD GVFAAGDAER GPSLIVWAIG SGRDVARHVD LHLTGETDLP
PSLETPNEPL VQ
//
