ID S6GTP3_9GAMM Unreviewed; 665 AA.
AC S6GTP3;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
DE AltName: Full=Beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00030512};
DE AltName: Full=N-acetyl-beta-glucosaminidase {ECO:0000256|ARBA:ARBA00033000};
GN ORFNames=OFPI_06970 {ECO:0000313|EMBL:EPJ54450.1};
OS Osedax symbiont Rs2.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae.
OX NCBI_TaxID=1330035 {ECO:0000313|EMBL:EPJ54450.1, ECO:0000313|Proteomes:UP000014830};
RN [1] {ECO:0000313|EMBL:EPJ54450.1, ECO:0000313|Proteomes:UP000014830}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Rs2 {ECO:0000313|Proteomes:UP000014830};
RA Yi H., Goffredi S.;
RT "Comparative genomics of two novel heterotrophic symbionts of deep-sea
RT Osedax worms: functional variation and environmental selection.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPJ54450.1}.
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DR EMBL; ASZI01000042; EPJ54450.1; -; Genomic_DNA.
DR AlphaFoldDB; S6GTP3; -.
DR PATRIC; fig|1330035.3.peg.663; -.
DR Proteomes; UP000014830; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06563; GH20_chitobiase-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000014830}.
FT DOMAIN 162..279
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 282..628
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 456
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 665 AA; 74944 MW; 1DEA7DB227F31F27 CRC64;
MSQLKLTISL REKHLQHNTS AASIVTQLDF SLTNLTGELV SIDKLATTFI YPIDPTSFVN
AQVLTHSGTY LEFAGQSVEP ILLQSGQSWT FSGDASAVLN QYSDMPAGFF VLSEGKVIDV
QYTKEDKLAT RISRIQPDSG AAEEQVVAAD NPDTRINSRA INCFPVPNSI VMTQGTADLS
QGFVLKAHSQ LQSQFYCMQN IEAQLACVDK MFYLAEQGLA LEIQLDVALV SEAYQLNISA
LGVVIKASER AGVHNALVSL WQIASLQSHS VPCLRIDDAP RFEWRGQHLD SARVYYSIAE
IKTFINHMSL YKLNKFHWHL VDDEAWRMQV NAYPQLCNNI AKRGWGELVE PQYGSGAQAS
GGYYTHRQMR EIVDYAAQRN IEVIPEIDIP GHCYALLKVL PELSEPEDQS VYQSVQGYRN
NCLNPALPAT YQFLENVFKE LVDIFPSQYV HIGADERPQG SWQKSPKITA LMKEQGFNSS
DQVQSYFLNK VQQILARLGK KTAAWEEATE QGELPKEGYI VSWKGTAAGI SALKRGYQVV
MAPAQHCYFD VAQSRHWDEP GLTWIGDWVG LQQVYNYNPV SDAIPAKLLG NLKGIQGCLW
SENLYDKSIL EHQLFPRIIA LAEISWSELR HQDYPRFHAD LKQFHQPMLD ALQISYRRRD
FDCDQ
//
