ID S6HFV6_9GAMM Unreviewed; 721 AA.
AC S6HFV6;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Diguanylate cyclase/phosphodiesterase {ECO:0008006|Google:ProtNLM};
GN ORFNames=OFPII_11850 {ECO:0000313|EMBL:EPJ47550.1};
OS Osedax symbiont Rs1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae.
OX NCBI_TaxID=1330036 {ECO:0000313|EMBL:EPJ47550.1, ECO:0000313|Proteomes:UP000014822};
RN [1] {ECO:0000313|EMBL:EPJ47550.1, ECO:0000313|Proteomes:UP000014822}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Rs1 {ECO:0000313|Proteomes:UP000014822};
RA Yi H., Goffredi S.;
RT "Comparative genomics of two novel heterotrophic symbionts of deep-sea
RT Osedax worms: functional variation and environmental selection.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPJ47550.1}.
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DR EMBL; ASZJ01000060; EPJ47550.1; -; Genomic_DNA.
DR AlphaFoldDB; S6HFV6; -.
DR PATRIC; fig|1330036.3.peg.1128; -.
DR Proteomes; UP000014822; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014822};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 199..260
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 321..458
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 466..717
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 721 AA; 80893 MW; A4F0747D15172275 CRC64;
MNKFKDGIGL RLLRYVFGCY LIVTILVTSA QLISEYSRAK SNIFSQTYEL EASFKDSLVS
SMWSFDTPQL KVTLAGVTKI DIVAGIKIMT DKNKMLASSG DVVSADSQIL SSTDLLAGIK
KIELIQADSS KHQTLFEYKF PLKHRESNSD PLKLIGYGYI YTDANTIIDR VKFSFILIII
NSLIKTAALW LLFLYFVNRF IAKPLAALAN AAEALNPDKL ETLCSSKELD NVVKAKHSDE
LYLLATNFDQ MRIAVLDKMA VIESQKCQLE ERVLARTKSL SEANDELRHL ALHDALTTLP
NRTLFKDRLE QFIKVGQRNN TRFIVASIDL SDFKSINDNY GHQIGDLILV EVARRLANAF
RKTDTVARMG GDEFYALLSL ERDDYSDVES LVQKFIKALE KPIHCDCENI PDILISANIG
TAIYPLHGED SAALIKNADM AMYHAKKSGI PHLLYSAKED LRLRRQSQLA QDLNIAIQNN
ELFLVYQPIL HLASNRITKI EVLVRWQHPT LGIISPVEFI PICERTGSIH QLTQWVFQQA
CTQCKPYCDV DESLSISINL SGRVFSQPQI PHILENICKR SNISPFNINL EVTETTAMEK
PEQAIEIMHQ LTGKGFTISI DDFGTGYSSL SYLVMLPVKE LKIDKSFLLS LGVNSEKVIK
AMIDLAHSLD LKVVGEGVET KALLDMLGVM GCDYAQGYYI AMPLSADQLD SFLYPQSVLK
T
//
