ID S7MIS6_MYOBR Unreviewed; 921 AA.
AC S7MIS6;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE SubName: Full=WD repeat-containing protein 47 {ECO:0000313|EMBL:EPQ03866.1};
GN ORFNames=D623_10030101 {ECO:0000313|EMBL:EPQ03866.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ03866.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
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DR EMBL; KE161437; EPQ03866.1; -; Genomic_DNA.
DR RefSeq; XP_005860140.1; XM_005860078.2.
DR AlphaFoldDB; S7MIS6; -.
DR GeneID; 102251272; -.
DR CTD; 22911; -.
DR eggNOG; KOG0641; Eukaryota.
DR OrthoDB; 76273at2759; -.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR006595; CTLH_C.
DR InterPro; IPR006594; LisH.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR040067; WDR47.
DR PANTHER; PTHR19863; NEMITIN (NEURONAL ENRICHED MAP INTERACTING PROTEIN) HOMOLOG; 1.
DR PANTHER; PTHR19863:SF5; WD REPEAT-CONTAINING PROTEIN 47; 1.
DR Pfam; PF17814; LisH_TPL; 1.
DR Pfam; PF00400; WD40; 6.
DR SMART; SM00668; CTLH; 1.
DR SMART; SM00667; LisH; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50897; CTLH; 1.
DR PROSITE; PS50896; LISH; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 45..102
FT /note="CTLH"
FT /evidence="ECO:0000259|PROSITE:PS50897"
FT REPEAT 659..689
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 753..793
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 798..839
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 840..874
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 886..921
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 392..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 501..596
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 501..568
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 921 AA; 102495 MW; 20B8DE32C9B43FC7 CRC64;
MTAEETVNVK EVEIIKLMLD FLNSKKLHIS MLALEKESGV INGLFSDDML FLRQLILDGQ
WDEVLQFIQP LECMEKFDKK RFRYIILKQK FLEALCVNNA MSSEDEPQHL EFTMQEAVQC
LHALEEYCPS KDDYSKLCLL LTLPRLTNHA EFKDWNPSTA RVHCFEEACV MVAEFIPADR
KLSEAGFKAS NNRLFQLVMK GLLYECCVEF CQSKATGEEI TESEVLLGID LLCGNGCDDL
DLSLLSWLQN LPSSVFSCAF EQKMLNIHVD KLLKPTKAAY ADLLTPLISK LSPYPSSPMR
RPQSADAYMT RSLNPALDGL TCGLTSHDKR ISDLGNKTSP MSHSFANFHY PGVQNLSRSL
MLENTECHSI YEESPERSDT PVEAQRPINS EILGQSSVSE KEPANGAQNP GPDRQEKNEL
RDSTEQFQEY YRQRLRYQQH LEQKEQQRQI YQQMLLEGGV NQEDGPDQQQ NLTEQFLNRS
IQKLGELNIG MDSLGSEVST LNQQCNGSKS NGSNNSSIIS FSTPPQDSSQ RLTHDASNIY
TSTPRNPGST NHIPFPEESS SCGNQVSSEH LVIKPPPGDS SGNLSRSRGE EDDKSKKQFV
CINTLEDTQA VRAVAFHPGG GLYAVGSNSK TLRVCAYPEV IDPSAHDIPK QPVVRFKRNK
HHKGSIYCVA WSPCGQLLAT GSNDKYVKVL PFNAETCNAT GPDLEFSMHD GTIRDLAFME
GPESGGAILI SAGAGDCNIY TTDCQRGQGL HALSGHTGHI LALYTWSGWM IASGSQDKTV
RFWDLRVPSC VRVVGTTLHG TGSAVASVAV DPSGRLLATG QEDSSCMLYD IRGGRMVQSY
HPHSSDVRSV RFSPGAHYLL TGSYDMKIKV TDLQGDLTKQ LPIMVVGEHK DKVIQCRWHT
QDLSFLSSSA DRTVTLWTYR G
//
