ID   S7NCS4_MYOBR            Unreviewed;       544 AA.
AC   S7NCS4;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   24-JAN-2024, entry version 41.
DE   SubName: Full=ETS-related transcription factor Elf-2 {ECO:0000313|EMBL:EPQ14871.1};
GN   ORFNames=D623_10033258 {ECO:0000313|EMBL:EPQ14871.1};
OS   Myotis brandtii (Brandt's bat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC   Myotis.
OX   NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ14871.1, ECO:0000313|Proteomes:UP000052978};
RN   [1] {ECO:0000313|Proteomes:UP000052978}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23962925; DOI=10.1038/ncomms3212;
RA   Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA   Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA   Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA   Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA   Krogh A., Wang J., Gladyshev V.N.;
RT   "Genome analysis reveals insights into physiology and longevity of the
RT   Brandt's bat Myotis brandtii.";
RL   Nat. Commun. 4:2212-2212(2013).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC   -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC       ECO:0000256|RuleBase:RU004019}.
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DR   EMBL; KE164069; EPQ14871.1; -; Genomic_DNA.
DR   RefSeq; XP_005877794.1; XM_005877732.2.
DR   AlphaFoldDB; S7NCS4; -.
DR   GeneID; 102248181; -.
DR   CTD; 1998; -.
DR   eggNOG; KOG3804; Eukaryota.
DR   OrthoDB; 4245771at2759; -.
DR   Proteomes; UP000052978; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR046328; ETS_fam.
DR   InterPro; IPR022084; TF_Elf_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11849; ETS; 1.
DR   PANTHER; PTHR11849:SF10; ETS-RELATED TRANSCRIPTION FACTOR ELF-2; 1.
DR   Pfam; PF12310; Elf-1_N; 1.
DR   Pfam; PF00178; Ets; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR   PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW   Nucleus {ECO:0000256|RuleBase:RU004019};
KW   Reference proteome {ECO:0000313|Proteomes:UP000052978}.
FT   DOMAIN          159..241
FT                   /note="ETS"
FT                   /evidence="ECO:0000259|PROSITE:PS50061"
FT   REGION          97..152
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          312..331
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        97..116
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        313..331
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   544 AA;  58432 MW;  A934560B9A1BC79E CRC64;
     MCSSSASPGI NMATSLHEGP TNQLDLLIRA VEASVHSSNA HCTDKTIEAA EALLHMESPT
     CLRDSRSPVE VFVPPCVSTP EFIHAAMRPD VITETVVEVS TEESEPMDTS PIPTSPDSHE
     PMKKKKVGRK PKTQQSPISN GSPELGIKKK PREGKGNTTY LWEFLLDLLQ DKNTCPRYIK
     WTQREKGIFK LVDSKAVSKL WGKHKNKPDM NYETMGRALR YYYQRGILAK VEGQRLVYQF
     KDMPKNIVVI DDDKSETCNE DLAAATDEKS LERVSLSAES LLKATSVRGG KNSSPLNCSR
     AEKGVARVVN ITSPGHDASS RSPTTTTSVS ATAAPRTVRV AMQVPVVMTS LGQKISTVAV
     QSVNAGAPLI TSTSPTTATS PKVVIQTIPT VMPASTENGD KITMQPAKII TIPATQLAQC
     QLQTKSNLTG SGSINIVGTP LAVRALTPVS IAHGAPVMRL SVPTQQASGQ TPPRVISAVI
     KGPEVKSEAV TIKQEHDVKT LQLVQEEKPA DGNKTVTHVV VVSAPSAIAL PVTMKTEGLV
     TCEK
//