ID S7NEE9_MYOBR Unreviewed; 424 AA.
AC S7NEE9;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Regulator of nonsense transcripts 3A {ECO:0000313|EMBL:EPQ14845.1};
GN ORFNames=D623_10005248 {ECO:0000313|EMBL:EPQ14845.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ14845.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
CC -!- SIMILARITY: Belongs to the RENT3 family.
CC {ECO:0000256|ARBA:ARBA00005991}.
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DR EMBL; KE164066; EPQ14845.1; -; Genomic_DNA.
DR AlphaFoldDB; S7NEE9; -.
DR eggNOG; KOG1295; Eukaryota.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR CDD; cd12727; RRM_like_Smg4_UPF3A; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR039722; Upf3.
DR InterPro; IPR005120; UPF3_dom.
DR PANTHER; PTHR13112:SF2; REGULATOR OF NONSENSE TRANSCRIPTS 3A; 1.
DR PANTHER; PTHR13112; UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN; 1.
DR Pfam; PF03467; Smg4_UPF3; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000052978}.
FT DOMAIN 9..164
FT /note="UPF3"
FT /evidence="ECO:0000259|Pfam:PF03467"
FT REGION 190..424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..245
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..332
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..376
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..424
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 424 AA; 49688 MW; BEE3C6B9B7FEFE33 CRC64;
MQVAFLLAVV IRRLPPSLTK EQLEEQLHPL PAHDYFEFFT GDLSLYPHLY SRAYINFRNP
DDILLFRDRF DGYIFIDNKG LEYPAVVEFA PFQKIAKKKL KKKDAKTGSI DDDPEYKKFL
ETYCVEEEKT SANPETLLGD IEAKTRELIA RRTTPLLEYI KNRKLEKQRI REEKREERRR
RELEKKRIRE EEKRKKREEE KCKRKETDKQ KKAAEKEVRI KLLKKPEKGE EAATEKPKEP
GEDIESGEGQ WEASPGCAVG KAKPRESPLE ERREKSQNDS DKEQKDMERK FREKELETQR
YHLDDSRKLR AHYEFDKFSR RNEEEMKPGK GFTPDRGKTG SQDRGVPVEA AERPGREQKS
EDSPAPRKER VRNKDRPALP LYQPGARMRA RECGGRFSEE GRDGRRAEAE DSAGAGSKKS
KEAE
//
