ID S7NIS9_MYOBR Unreviewed; 1751 AA.
AC S7NIS9;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=AT-rich interactive domain-containing protein 2 {ECO:0000313|EMBL:EPQ17331.1};
GN ORFNames=D623_10029493 {ECO:0000313|EMBL:EPQ17331.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ17331.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
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DR EMBL; KE164352; EPQ17331.1; -; Genomic_DNA.
DR eggNOG; KOG2312; Eukaryota.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003150; DNA-bd_RFX.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR22970; AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR22970:SF14; AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF02257; RFX_DNA_binding; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51526; RFX_DBD; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000052978}.
FT DOMAIN 443..522
FT /note="RFX-type winged-helix"
FT /evidence="ECO:0000259|PROSITE:PS51526"
FT REGION 737..763
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 810..838
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 877..971
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1238..1259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1283..1384
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1405..1424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1505..1540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1619..1642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1290..1305
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1312..1327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1337..1384
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1623..1642
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1751 AA; 188598 MW; 4D15620C2D644B69 CRC64;
MYIYFKISTV LFFCFSYLEK YEKVHHFGED DDEVPPGNPK PQLPIGAIPS SYNYQQHSVS
DYLRQSYGLS MDFNSPNDYN KLVLSLLSGL PNEVDFAINV CTLLSNESKH VMQLEKDPKI
ITLLLANAGV FDDRSFSTVF GEEWKEKTDR DFVKFWKDIV DDNEVRDLIS DRNKSHEGTS
GEWIWESLFH PPRKLGINDI EGQRVLQIAV ILRNLSFEEG NVKLLAANRT CLRFLLLSAH
SHFISLRQLG LDTLGNIAAE LLLDPVDFKT THLMFHTVTK CLMSRDRFLK MRGMEILGNL
CKAEDNGVLI CEYVDQDSYR EIICHLTLPD VLLVISTLEV LYMLTEMGDV ACTKIAKVEK
SIDMLVCLVS MDIQMFGPDA LAAVKLVEHP SSSHQVLSEI RTQAVEQVQT QIHVAAAPAS
RAVVAQHVAP PPGIVEIDSE KFACQWLNAH FEVNPDCSVS RAEMYSEYLS TCSKLARGGI
LTSTGFYKCL RTVFPNHSVK RVEDSSNSGQ AHIHVVGVKR RAIPLPIQMY YQQQPVSTPV
VRVDSVPDIS TSPSPAGIPH GPQTVGNHFQ RTPVTNQSSN LTATQMSFPV QGVHTMAQTV
SRIPPNPSVH THQQQNAPVT VIQNKAPIPC EVVKATMIQN SIPQTAVPVS IAVGGGAAQS
SVVQNHSTGP QPVTVVNSQT LLHHPSVIPQ QSPLHTVVPG QIPSGTPVTV IQQTVPQSHI
FGRVQTMPAC TSTVSQGQQL ITTSPQPVQT SSQQTSAGSQ PQDTVIIAPP QYVTTSASNI
VSATSVQNFQ VATGQMVTIA GVPSPQPSRV GFQNIAPKPL PSQQVSSTVV QQPIQQPQQP
TQQSVVIVSQ PAQQGQTYAP AIHQIVLANP AALPSGQTVQ LTGQPNITPS SSPSPVPASN
NQVPTAMSSS STPQSQGPPP TVSQMLSVKR QQQQHSPAPP PQQVQVQVQQ PQVQMQVQPQ
QTNAVGQPAS GESSLIKQLL LPKRGPSTPG GKLILPAPQV PPPNNARAPS PQVVYQVANN
QAAGFGMQGQ TPAQQLLVGQ QNVQLVQGAM PSTGGVQTVP ISNLQILPGP LISNSPATIF
QGTSGNQVTI TVVPNTSFAT ATVSQGNATQ LIAPAGITMS GTQAGVGLQV QTLPASQASP
AGQSSCTTAT PPFKGDKIIC QKEEEAKEAT GLHVHERKIE VMENPSCRRG TMNTSNGDTK
ENEMQVGSLL NGRKYSDSSL PPSNSGKIQS EANQCSLISN GPSLELGENG ASGKQNSEQV
DMQDIKSDLR KPLVNGICDF DKGDGSHLSK NIPNHKTSNH VGNGEISPME PQGTLDATQQ
DTAKGDQLER ISNGPVLTLG GSPSVSSIQE TSNVATQQFS GTDLPNGPLT SSLNSDVPQQ
RPSVVVSPHS TTSVIQGHQI IVPHSGSRVS HSPALPSDVR STNGTAECKT VKRPAEDNDR
ETVTGIPNKV GVRIVTISDP NNAGCSATMV AVPAGADPST VAKVAIESAV QQKQQQPSSY
IQNVVPQNTP MTPSPAVQVQ SQPNSSQPSP FSASSQHGDS VRKPGHNFMC LWQSCKKWFQ
TPSQVFYHAA TEHGGKDVYP GQCLWEGCEP FQRQRFSFIT HLQDKHCSKD ALLAGLKQDE
PGQAGSQKPS TKQPVVGGTS STPRAQKAIV NHPSAALMAL RRGSRNLVFR DFTDEKEGPI
TKHIRLTAAL ILKNIGKYSE CGRRLLKRHE NNLSVLAISN MEASSTLAKC LYELNFTVQS
KEQEKDSEML Q
//
