ID S7NWF8_MYOBR Unreviewed; 577 AA.
AC S7NWF8;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Poliovirus receptor-related protein 3 {ECO:0000313|EMBL:EPQ01958.1};
DE Flags: Fragment;
GN ORFNames=D623_10006374 {ECO:0000313|EMBL:EPQ01958.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ01958.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
CC -!- SIMILARITY: Belongs to the nectin family.
CC {ECO:0000256|ARBA:ARBA00007810}.
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DR EMBL; KE161130; EPQ01958.1; -; Genomic_DNA.
DR AlphaFoldDB; S7NWF8; -.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR GO; GO:0046718; P:viral entry into host cell; IEA:InterPro.
DR CDD; cd07704; IgC1_2_Nectin-3-4_like; 1.
DR CDD; cd05887; IgV_1_Nectin-3_like; 1.
DR CDD; cd12087; TM_EGFR-like; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR033320; IgC1_2_Nectin-3-4-like.
DR InterPro; IPR033319; Nectin-3_IgV_dom.
DR PANTHER; PTHR23277:SF12; NECTIN-3; 1.
DR PANTHER; PTHR23277; NECTIN-RELATED; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 3.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:EPQ01958.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..577
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004543468"
FT TRANSMEM 360..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 506..530
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 10..124
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 129..217
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 228..313
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EPQ01958.1"
SQ SEQUENCE 577 AA; 64237 MW; 6CFEC95C5D166E75 CRC64;
IFLRTIFFFP PIGALAGPII VEPHVTAVWG KNVSLKCLIE VNETITQISW EKVHGKGSQT
VAVHHPQYGF SVQGEYQGRV LFKNYSLNDA TITLHNIGFS DSGKYICKAV TFPLGNAQSS
TTVTVLVEPT VSLIKGPDSL IDGGNETVAA ICIAATGKPV AHINWEGDLG EMESTTTSFP
NETATIVSQY KLFPTRFARG RRITCVVKHP ALEKDIRYSF ILDIQYAPEV SVTGYDGNWF
VGRKGVNLKC NADANPPPFK SVWSRLDGQW PDGLLASDNT LHFVHPLTFN YSGVYVCKVT
NSLGQRSDQK VIYISDPPTT TTLQPTVQWH LSTADIEDLT KDVKKLPFPL STLATIKDDA
IGTIIASVVG GALFVILVSV LGGIFCYRRR RTFRGDYFAK NYIPPSDMQK ESQIDVLQQD
ELDSYPDSVK KENKNPVNNL IRKDYLEEPE KTQWNNVENL RFERPMDYYE DLKMGMKFVS
DEHYDENEDD LVSHVDDVPF KPTSSIAIAG AVIGAVLALL IIAVFVTVLL TPRKKRPSYL
DKVIDLPPTH KPPPVYEKRS PPLPQKDLLY QLIGNGN
//
