ID S7NYQ0_MYOBR Unreviewed; 653 AA.
AC S7NYQ0;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Transcription initiation factor TFIID subunit 6 {ECO:0000256|ARBA:ARBA00040091};
GN ORFNames=D623_10009889 {ECO:0000313|EMBL:EPQ02803.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ02803.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TAF6 family.
CC {ECO:0000256|ARBA:ARBA00007688}.
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DR EMBL; KE161261; EPQ02803.1; -; Genomic_DNA.
DR AlphaFoldDB; S7NYQ0; -.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0000124; C:SAGA complex; IEA:InterPro.
DR GO; GO:0046695; C:SLIK (SAGA-like) complex; IEA:InterPro.
DR GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0016251; F:RNA polymerase II general transcription initiation factor activity; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR CDD; cd08050; TAF6C; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR Gene3D; 1.25.40.770; TAF6, C-terminal HEAT repeat domain; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR037796; TAF6.
DR InterPro; IPR011442; TAF6_C.
DR InterPro; IPR046344; TAF6_C_sf.
DR InterPro; IPR004823; TAF_TATA-bd_Histone-like_dom.
DR PANTHER; PTHR10221; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6; 1.
DR PANTHER; PTHR10221:SF9; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6; 1.
DR Pfam; PF02969; TAF; 1.
DR Pfam; PF07571; TAF6_C; 1.
DR SMART; SM00803; TAF; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|EMBL:EPQ02803.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein biosynthesis {ECO:0000313|EMBL:EPQ02803.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 12..78
FT /note="TATA box binding protein associated factor (TAF)
FT histone-like fold"
FT /evidence="ECO:0000259|SMART:SM00803"
FT REGION 142..195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 550..576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 653 AA; 71579 MW; AA46F68F47DED2B1 CRC64;
MAEEKKLKLS NTVLPWEPMK VVAESMGIAQ IQDETCQLLA DEVSYRIKEI AQDALKFMHM
GKRRKLTTSD IDYALKLKNV EPLYGFHAQE FIPFRSASGG GRELYFYEEK EVDLSDIINT
PLPRVPLDVC LKAHWLSIEG CQPAIPENPP PAPKERQKAE ATEPPKSAKP GQEEGGPLQS
KGPGAALADG KGNAKKKARP LLQGAPFRLK PQSSHELSVE QQLYYKVITE ACVGSCEAKR
AEALQSIATD PGLYQMLPRF SIFISEGVRV NVVQNNLALL IYLMRMVKAL MDNPTLYLEK
YVHELIPAVM TCIVSRQLCL RPDVDNHWAL RDFAARLVAQ ICKHFSTTTN NIQSRITKTF
TKSCVDEKTP WTTRYGSIAG LAELGHDVIK TLILPRLQQE GEQIRSVLDG PVLSNIDRIV
ADHVQSLLLK HCAPVLAKLR PPPDNQDAYR AEFGSLGPLL CSHVVKARAQ AALQAQQVNR
TTLTITQTRP TLTLSQAPQP GPQTPGLLKV PGSIALPVQT LVSARAAVPP QPSPPPTKFI
VMSSSSSASS IQQGAKHLGH PKSTGHPATG ESGSPHGKPC CLKAFLPGAQ LPSVICCLKD
VPITARRAAQ ILSFSYRQPS ETALLGSRKT LKLFLVKSPD WKILESHEEG KTL
//
