ID S7P6Z9_MYOBR Unreviewed; 1873 AA.
AC S7P6Z9;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Methyl-CpG-binding domain protein 5 {ECO:0000313|EMBL:EPQ03382.1};
GN ORFNames=D623_10035492 {ECO:0000313|EMBL:EPQ03382.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ03382.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
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DR EMBL; KE161360; EPQ03382.1; -; Genomic_DNA.
DR eggNOG; ENOG502QTC7; Eukaryota.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR CDD; cd20141; PWWP_MBD5; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR InterPro; IPR001739; Methyl_CpG_DNA-bd.
DR InterPro; IPR000313; PWWP_dom.
DR PANTHER; PTHR16112; METHYL-CPG BINDING PROTEIN, DROSOPHILA; 1.
DR PANTHER; PTHR16112:SF18; METHYL-CPG-BINDING DOMAIN PROTEIN 5; 1.
DR SMART; SM00391; MBD; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50982; MBD; 1.
DR PROSITE; PS50812; PWWP; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000052978}.
FT DOMAIN 11..81
FT /note="MBD"
FT /evidence="ECO:0000259|PROSITE:PS50982"
FT DOMAIN 1624..1719
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT REGION 123..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 200..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 451..521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 594..694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1028..1050
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1390..1420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1586..1614
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1821..1873
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 126..140
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 222..236
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 256..271
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..471
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 497..512
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 594..634
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 661..694
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1835..1865
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1873 AA; 199437 MW; 8C369A3D5D79020F CRC64;
MNGGKECDGG DKDGGLPAIQ VPVGWQRRVD HNGVLYVSPS GSLLSCLEQV KTYLLTDGTC
KCGLECPLIL PKVFNFDPGA AVKQRTAEDV KADEDVTKLC IHKRKIIAVA TLHKSMEAPH
PSLVLTSPGG GTNATPVVPS RAATPRSVRN KSHEGITNSV MPECKHPFKL MMGSSNAMGR
LYVQELPGSQ QQELHPVYPR QRLGSSEHGQ KSPFRGSHGG LPSPASSGSQ IYGDGSISPR
TDPLGSPDVF TRNNPGFHGA PNSSPIHLNR TPLSPPSVML HGSPVQSSCA MAGRTNIPLS
PTLTTKSPVM KKPMCNFSNN MEIPRAMFHH KLPHGPPPPP PPSCALQKKP LTSEKDPLGI
LDPIPSKPAN QNPVIINPTS FHSNVHSQVP VMNVSMPPAV VPLPSNLPLP TVKPGHMNHG
SHVQRVQHSA STSLSPSPVT SPVHMMGAGI GRIEASPQRS RSSSTSSDHG NFMMPPLGPQ
AACSGIKVPP RSPRSTIGSP RPSMPSSPST KSDGHHQYKD IPNPLIAGMS NVLTTPSSAA
FPAAPAGSGS VKSQPGLLGM PLNQILNQHN AASFPASSLL SAAAKAQLAN QNKLASNNSS
SSSNSGAVAG SGNTEGHSTL NTMFPPTANM LLPTGEGQSG RAALRDKLMS QQKDSLRKRK
QPPTTVLSLL RQSQMDSSSV PKPGPDSLRK QSQGSFPISS MSQLLQSMSC QSSHLSSNST
PGCGASNTAL PCSANQLHFT DPSVNSSVLQ NSLTQNIPVR GEAVHCHNAN TNFVHSHNSV
PNHHLAGLIN QIQASGNCGM LSQSGMALGN SLHPNPPQSR ISTSSTPVIP NSIVSSYNQT
SSEAGGSGPS SSIAIAGTSH PAITKTTSVL QDGVIVTTAA GNPLQSQLPI GSDFPFVGQE
HALHFPSNST SNNHLPHPLN PSLLSSLPIS LPVNQQHLLN QNLLNILQPS AGEGKSEINL
HPLGFLNPNV NAALAFLSGD MDGQGLQPVH FQLLAALLQN QAHAAAMLPL PSFNLTISDL
FQQQNTPLPS LTQMTAPPDH LPSNQSENSR AETLLTSPLG NPLPSFAGSD TTFNPLFLPA
VTGASGLMAL NPQLLGGVLN SASANTANHP EVSIATSSQA TTTTTTTSSA VAALTVSTLG
GTAVVSMAET LLNVSNSAGN TPGPAKLNSN SVVPQLLNPL LGTGLLGDMS SINNTLNNHQ
LTHLQSLLNN NQMFPPNQQQ QQQILQGYPN LQAFQGQPTI PCPANNNPMA CLFQNFQVRM
QEDAALLNKR TSTQPGLTAL PENPNTTLPP FQDTACELQP RIDPSLGQQV KDGLIVGGQG
DASVDAIYKA VVDAASKGMQ VVITTAVNST TQISPIPALS AMSAFTASIG DPLSLPSAVS
AVIHGRNMGN VDHDGRLRNA RGPRLPRNPD HGKNSHEGDG FEYFKSATCH ASKKQWDGEQ
SPGGERNRWK CEEFLDHPGH IHSSPCHERP NNVSTLPFLP GEQHPILLPP RNCQGDKILE
ENFRYNNYKR TMMSFKERLE NTVERCAHIN GNRPRQSRGF GELLSTTKQD LVLGEQSPSS
SNSLESSLVK DYIHYNGDFN AKSINGCVPS PSDAKSISSE DDLRNPDSPS SNELIHYRPR
TFNVGDLVWG QIKGLTSWPG KLVREDDVHN LWEMVSKTEI EIIGVSGKGT SPPPRSPATI
WWPHCNEVEA PQRVVVLEQD RGEDRPKVEP EKLKTLTEGL EAYSRARKRN RKSGKLNNHL
EAAIHEAMSE LDKMSGTNWK QKFTEAGEGG VREAAWRMDW LSVDKPSAQP SRQRRRDTVL
SPFSWISSSS HVSKAIMEQV LKSPEPPRPP WPLENQAVSS DSVFSPLAPP DTLPSNSNSV
RPSGLASSPR HLG
//
