ID S7P9X0_MYOBR Unreviewed; 456 AA.
AC S7P9X0;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Equilibrative nucleoside transporter 1 {ECO:0000313|EMBL:EPQ04442.1};
GN ORFNames=D623_10026100 {ECO:0000313|EMBL:EPQ04442.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ04442.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
CC -!- SUBCELLULAR LOCATION: Basolateral cell membrane
CC {ECO:0000256|ARBA:ARBA00004554}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004554}. Lateral cell membrane
CC {ECO:0000256|ARBA:ARBA00034693}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00034693}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
CC {ECO:0000256|ARBA:ARBA00007965}.
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DR EMBL; KE161549; EPQ04442.1; -; Genomic_DNA.
DR RefSeq; XP_005861018.1; XM_005860956.2.
DR RefSeq; XP_005861019.1; XM_005860957.2.
DR RefSeq; XP_014390858.1; XM_014535372.1.
DR AlphaFoldDB; S7P9X0; -.
DR GeneID; 102261544; -.
DR KEGG; myb:102261544; -.
DR CTD; 2030; -.
DR eggNOG; KOG1479; Eukaryota.
DR OrthoDB; 517168at2759; -.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016328; C:lateral plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015213; F:uridine transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR034764; ENT1/ENT2.
DR InterPro; IPR002259; Eqnu_transpt.
DR NCBIfam; TIGR00939; 2a57; 1.
DR PANTHER; PTHR10332; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER; 1.
DR PANTHER; PTHR10332:SF9; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1; 1.
DR Pfam; PF01733; Nucleoside_tran; 1.
DR PIRSF; PIRSF016379; ENT; 1.
DR PRINTS; PR01130; DERENTRNSPRT.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 430..452
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 456 AA; 49881 MW; 8EC668A17070C272 CRC64;
MTTSHQPQDR YKAVWLIFFM LGLGTLLPWN FFMTATLYFT SRLGQPQNVS LGTANLSRDI
QASATPMVPS PDRNYLSAIF NNVMTLCAML PLLIFTCLNS FLHQRIPQSV RILGSLVAIL
LVFLITAILV RVPLDALPFF VITMIKIMLI NSFGAILQGS LFGLAGLLPA HYTAPIMSGQ
GLAGIFAAVA MICAIASGSE LSESAFGYFI TACGVIILTI ICYLGLPRLE FYRYYQQLKL
EGPGEQETKL DLISKGEASR AGKEEFGVSA PNSQPTNNSP SIRAILKNIL VPALSVCFIF
TVTIGVFPAV TSDAKSSIAG SSAWGRYFIP VSCFLTFNVF DWLGRSLTTI TMWPGKDSRW
LPILVVARLV FVPLLLLCNV HPRKYLAVIF KHDAWYIIFM AAFAFSNGYL ASLCMCFGPK
KVKPAEAETA GAIMAFFLSL GLALGAVFSF LFRAIV
//
