ID S7PMZ5_MYOBR Unreviewed; 441 AA.
AC S7PMZ5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Tumor necrosis factor receptor superfamily member 1B {ECO:0000313|EMBL:EPQ12233.1};
DE Flags: Fragment;
GN ORFNames=D623_10022032 {ECO:0000313|EMBL:EPQ12233.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ12233.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
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DR EMBL; KE163474; EPQ12233.1; -; Genomic_DNA.
DR AlphaFoldDB; S7PMZ5; -.
DR eggNOG; ENOG502RZ23; Eukaryota.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005031; F:tumor necrosis factor receptor activity; IEA:InterPro.
DR GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR CDD; cd10577; TNFRSF1B; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 2.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR InterPro; IPR020411; TNFR_1B.
DR InterPro; IPR033996; TNFRSF1B_N.
DR PANTHER; PTHR47386; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1B; 1.
DR PANTHER; PTHR47386:SF1; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1B; 1.
DR Pfam; PF00020; TNFR_c6; 3.
DR PRINTS; PR01919; TNFACTORR1B.
DR SMART; SM00208; TNFR; 4.
DR SUPFAM; SSF57586; TNF receptor-like; 2.
DR PROSITE; PS00652; TNFR_NGFR_1; 2.
DR PROSITE; PS50050; TNFR_NGFR_2; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00206};
KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:EPQ12233.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 242..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 18..54
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 18..54
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 56..97
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 56..97
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 98..140
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 98..140
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REGION 194..217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 283..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 374..441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..333
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 340..357
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 374..392
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 33..46
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 36..54
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 57..72
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 79..97
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 122..140
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EPQ12233.1"
SQ SEQUENCE 441 AA; 45870 MW; B9870E136A8BF984 CRC64;
SSPFQAVFTP YAPEDGSSCQ RREYYDERAQ MCCSMCPPGY HVQSSCTKTS DTVCAPCEDS
MYTELWNWVP ECLSCSSRCS SELVEAQACT REQNRVCACR PGWYCVLKSQ HRCQVCAPLR
KCPPGFGVVA PGTPTSNVVC AACAPGTFSD TASSTDTCRP HRFCESTAIP GNASMDAVCT
PVLPSLRVTT SLALKPQAAS TKSQPMEPTP GPSTTASMSV LLPVVPSAPA EGLSTGNISL
PVGLIVGVTA LGLLMIGLLN CVILAQKKKK PFCLPGDAKP HLPADKAQAA PGSEQQHLLT
TAPSSSSSSL ESAASASHRG TPTRNQPQAP GRDQPTGSGE ARAGSGSSES SPGGHGTHVN
VTCIVNVCSS SDHSSRCSSQ ASSTTGNADP SPSGSPKDEH VPFSKEECPV RSPRGAPETL
LQSLEEKPLN LGVPDAGMKP S
//
