ID S7PPK7_MYOBR Unreviewed; 744 AA.
AC S7PPK7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Putative G-protein coupled receptor 149 {ECO:0000313|EMBL:EPQ12788.1};
GN ORFNames=D623_10024451 {ECO:0000313|EMBL:EPQ12788.1};
OS Myotis brandtii (Brandt's bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Vespertilionidae;
OC Myotis.
OX NCBI_TaxID=109478 {ECO:0000313|EMBL:EPQ12788.1, ECO:0000313|Proteomes:UP000052978};
RN [1] {ECO:0000313|Proteomes:UP000052978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23962925; DOI=10.1038/ncomms3212;
RA Seim I., Fang X., Xiong Z., Lobanov A.V., Huang Z., Ma S., Feng Y.,
RA Turanov A.A., Zhu Y., Lenz T.L., Gerashchenko M.V., Fan D., Hee Yim S.,
RA Yao X., Jordan D., Xiong Y., Ma Y., Lyapunov A.N., Chen G., Kulakova O.I.,
RA Sun Y., Lee S.G., Bronson R.T., Moskalev A.A., Sunyaev S.R., Zhang G.,
RA Krogh A., Wang J., Gladyshev V.N.;
RT "Genome analysis reveals insights into physiology and longevity of the
RT Brandt's bat Myotis brandtii.";
RL Nat. Commun. 4:2212-2212(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KE163588; EPQ12788.1; -; Genomic_DNA.
DR RefSeq; XP_005874474.1; XM_005874412.2.
DR AlphaFoldDB; S7PPK7; -.
DR GeneID; 102258552; -.
DR KEGG; myb:102258552; -.
DR CTD; 344758; -.
DR eggNOG; KOG0331; Eukaryota.
DR OrthoDB; 5349609at2759; -.
DR Proteomes; UP000052978; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15011; 7tmA_GPR149; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR24229:SF32; G-PROTEIN COUPLED RECEPTOR 149-RELATED; 1.
DR PANTHER; PTHR24229; NEUROPEPTIDES RECEPTOR; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:EPQ12788.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000052978};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 33..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 49..373
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT COILED 706..740
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 744 AA; 82236 MW; BEE0DA65781509BD CRC64;
MSVFLNNLTN DSSLWKENHN STDLLNPPGT LNVYLFCLTC FLTLAALAGS IYSLVSLLKT
QNRTVVSMLV ASWCGDDLLS VLSVTIFMFL QWPNEVFDYF QSLCATSALL YLCQGLSSNL
KATLLVSYNF YTMHRTVGSQ AASRRSSQVL GVALTVWAAS LLLSALPLCG WGAFVRTPWG
CLADCSSSYV LLLFAVYTSA FGLLAGLSVP LIHQLLCSEE PLRLHAHYQE ISRGTSTPGT
PPTGERVLSL CPEDALGPAL RRFAGCSLNS DAVLGPGLPG RVEQERGPGR SATAGAGACR
HEDPGTLYGT RSFSVSTAQK RFSLILALTK VILWLPMMIH MVVQYMGGFQ SLPFESLSFL
LTLLATTVTP VFVLSKRWTH LPCGCIINCK RDAYAVASDG EKTKRNCFEF NLSFEQSYGI
YKIAHEDYYG DDGNSISYHN LMNYECRTPK DSQRDTPNIF SAIKVEISTT PSLDSSTLKG
INKYTNTDIT EAKQDSHNEK GVDPLLFEKT GDIHYEETTF LEGPERRLSH EESQKPDLSD
WEWCRSKSER TPRQRSGGGL AIPLCAFQGM VSLQAPTGKT LSLSTYEVST EGQKITPASK
KIEVYRSKSV GHEPNSEDSP STFADTSVKI HLEVLEICDN EEALDTVSII SNISQSSTQV
RSPSLRYSRK ENRFVSCDLG ETASYSLFLP TSNPDGNINI SIPDTVEAHR QNSKRQHQER
DGYQEEIQLL NQAYRKREEE SKGS
//
