ID S7Q6L1_GLOTA Unreviewed; 715 AA.
AC S7Q6L1;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Phenylalanine ammonium lyase {ECO:0000313|EMBL:EPQ55063.1};
GN ORFNames=GLOTRDRAFT_42132 {ECO:0000313|EMBL:EPQ55063.1};
OS Gloeophyllum trabeum (strain ATCC 11539 / FP-39264 / Madison 617) (Brown
OS rot fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Gloeophyllales; Gloeophyllaceae; Gloeophyllum.
OX NCBI_TaxID=670483 {ECO:0000313|EMBL:EPQ55063.1, ECO:0000313|Proteomes:UP000030669};
RN [1] {ECO:0000313|EMBL:EPQ55063.1, ECO:0000313|Proteomes:UP000030669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11539 {ECO:0000313|EMBL:EPQ55063.1,
RC ECO:0000313|Proteomes:UP000030669};
RX PubMed=22745431; DOI=10.1126/science.1221748;
RA Floudas D., Binder M., Riley R., Barry K., Blanchette R.A., Henrissat B.,
RA Martinez A.T., Otillar R., Spatafora J.W., Yadav J.S., Aerts A., Benoit I.,
RA Boyd A., Carlson A., Copeland A., Coutinho P.M., de Vries R.P.,
RA Ferreira P., Findley K., Foster B., Gaskell J., Glotzer D., Gorecki P.,
RA Heitman J., Hesse C., Hori C., Igarashi K., Jurgens J.A., Kallen N.,
RA Kersten P., Kohler A., Kuees U., Kumar T.K.A., Kuo A., LaButti K.,
RA Larrondo L.F., Lindquist E., Ling A., Lombard V., Lucas S., Lundell T.,
RA Martin R., McLaughlin D.J., Morgenstern I., Morin E., Murat C., Nagy L.G.,
RA Nolan M., Ohm R.A., Patyshakuliyeva A., Rokas A., Ruiz-Duenas F.J.,
RA Sabat G., Salamov A., Samejima M., Schmutz J., Slot J.C., St John F.,
RA Stenlid J., Sun H., Sun S., Syed K., Tsang A., Wiebenga A., Young D.,
RA Pisabarro A., Eastwood D.C., Martin F., Cullen D., Grigoriev I.V.,
RA Hibbett D.S.;
RT "The Paleozoic origin of enzymatic lignin decomposition reconstructed from
RT 31 fungal genomes.";
RL Science 336:1715-1719(2012).
CC -!- SIMILARITY: Belongs to the PAL/histidase family.
CC {ECO:0000256|ARBA:ARBA00007238, ECO:0000256|RuleBase:RU003954}.
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DR EMBL; KB469302; EPQ55063.1; -; Genomic_DNA.
DR RefSeq; XP_007866123.1; XM_007867932.1.
DR AlphaFoldDB; S7Q6L1; -.
DR SMR; S7Q6L1; -.
DR STRING; 670483.S7Q6L1; -.
DR GeneID; 19306110; -.
DR KEGG; gtr:GLOTRDRAFT_42132; -.
DR eggNOG; KOG0222; Eukaryota.
DR HOGENOM; CLU_014801_3_1_1; -.
DR OMA; GNFHGDY; -.
DR OrthoDB; 1030318at2759; -.
DR Proteomes; UP000030669; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0016841; F:ammonia-lyase activity; IEA:InterPro.
DR GO; GO:0006559; P:L-phenylalanine catabolic process; IEA:InterPro.
DR CDD; cd00332; PAL-HAL; 1.
DR Gene3D; 1.20.200.10; Fumarase/aspartase (Central domain); 1.
DR Gene3D; 1.10.275.10; Fumarase/aspartase (N-terminal domain); 1.
DR InterPro; IPR001106; Aromatic_Lyase.
DR InterPro; IPR024083; Fumarase/histidase_N.
DR InterPro; IPR008948; L-Aspartase-like.
DR InterPro; IPR022313; Phe/His_NH3-lyase_AS.
DR InterPro; IPR005922; Phe_NH3-lyase.
DR InterPro; IPR023144; Phe_NH3-lyase_shielding_dom_sf.
DR NCBIfam; TIGR01226; phe_am_lyase; 1.
DR PANTHER; PTHR10362; HISTIDINE AMMONIA-LYASE; 1.
DR PANTHER; PTHR10362:SF80; PHENYLALANINE AMMONIA-LYASE 2; 1.
DR Pfam; PF00221; Lyase_aromatic; 1.
DR SUPFAM; SSF48557; L-aspartase-like; 1.
DR PROSITE; PS00488; PAL_HISTIDASE; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|RuleBase:RU003954, ECO:0000313|EMBL:EPQ55063.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000030669}.
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 715 AA; 76656 MW; 31E01651BDCD680B CRC64;
MNGHSANGHA NGRATNGHAS PVKDSGLLPK FIDAVHELEY YRNGKPVKLD GHSLSIPAVV
AAARFNSPVT LDYSPEVQDR VAKSRDVIVE KVNGLKSVYG VSTGFGGSAD TRTSNTLALG
HALLQHQHSG VLPSSTKASS ALPLSDPLTS TSMPEAWVRG AILIRINSLI RGHSGVRWEL
IEKMVDLLRE DIVPLVPLRG SISASGDLAP LSYIAGTLTA NPSIRVFDGP RASGQRVIKS
SRDALREHKI EPVALQSKEH LGILNGTAFS ASVGALALSE AAHLALLAQV CTAMGVEALA
GTRGSFDPFI HDVARPHPGQ VESARMIHDL LEGSTFAITA EEEVTISEDK GHLRQDRYPL
RTAPQFLGPQ IEDILSALET VTLECNSTTD NPLVDGNTGT VHHGGNFQAM AVSNAMEKTR
LALHHIGKIL FAQSTELMNP TMNRGLPPNL ASTDPSLNYH TKGIDIATAA YVGELGYLAN
PVSTHVQSAE MHNQAVNSLA LISARATINA LEVLSMLISS YLYCLCQALD LRAMQAEFME
GVSKIVREEL STAFGSSLEG SSLEGLSSQI FSVVVDAFEE TSSMDAAPRM QHIAAQTTTA
LFDFLSSPAP QALASIPSFR DSLAKRSTDL LKQLRQDYLS GTRGPAPAIP YLSRTRPVYE
FIRVKLGVRM HGSENLHLWE NGAGVEDVTI GQNISSIYEA IRDGQMQEVV VGLFN
//
