ID S7V3T5_DESML Unreviewed; 320 AA.
AC S7V3T5;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Dehydrogenase E1 component {ECO:0000313|EMBL:EPR39333.1};
GN ORFNames=dsmv_2675 {ECO:0000313|EMBL:EPR39333.1};
OS Desulfococcus multivorans DSM 2059.
OC Bacteria; Thermodesulfobacteriota; Desulfobacteria; Desulfobacterales;
OC Desulfococcaceae; Desulfococcus.
OX NCBI_TaxID=1121405 {ECO:0000313|EMBL:EPR39333.1, ECO:0000313|Proteomes:UP000014977};
RN [1] {ECO:0000313|EMBL:EPR39333.1, ECO:0000313|Proteomes:UP000014977}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2059 {ECO:0000313|EMBL:EPR39333.1,
RC ECO:0000313|Proteomes:UP000014977};
RX PubMed=23950126;
RA Brown S.D., Hurt R.A.Jr., Gilmour C.C., Elias D.A.;
RT "Draft genome sequences for three mercury-methylating, sulfate-reducing
RT bacteria.";
RL Genome Announc. 1:e00618-e00613(2013).
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPR39333.1}.
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DR EMBL; ATHJ01000090; EPR39333.1; -; Genomic_DNA.
DR AlphaFoldDB; S7V3T5; -.
DR STRING; 897.B2D07_03425; -.
DR PATRIC; fig|1121405.3.peg.2332; -.
DR eggNOG; COG1071; Bacteria.
DR OrthoDB; 9766715at2; -.
DR Proteomes; UP000014977; Unassembled WGS sequence.
DR GO; GO:0016624; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; IEA:InterPro.
DR CDD; cd02000; TPP_E1_PDC_ADC_BCADC; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR001017; DH_E1.
DR InterPro; IPR029061; THDP-binding.
DR PANTHER; PTHR11516:SF60; PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA; 1.
DR PANTHER; PTHR11516; PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR; 1.
DR Pfam; PF00676; E1_dh; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000014977}.
FT DOMAIN 16..311
FT /note="Dehydrogenase E1 component"
FT /evidence="ECO:0000259|Pfam:PF00676"
SQ SEQUENCE 320 AA; 34420 MW; 589DDC6C5352A7D4 CRC64;
MEIPKAKKME MLRSLLLSRR FEETLTELCK IDGKIPGMMI LCTGQEAVGA GVCAALQPED
AIITNHRSHS HLLAKGADPN SLMAEIYGKR TGCNKGKSGT LHLAVPEINA PCTTTVVGGG
PPIAAGRAFA QQYRGEKSVT VCFIGDGAAN EGSFHEALNL ASVWHLPVIF VCENNLYAGA
QRYEEHTRVE HIADRAAGYA VPGVVVDGND ALAVYASAVD ARARAIAGKG PTLIEYKTYR
WRGHGESDLQ LYQPREEIAA WQAACPIPKL RGDMLAQGLI SADELAAMER AVEAVVKAAV
RFAEESPYPE PHEALEDVFA
//
