ID S8AEV6_DACHA Unreviewed; 699 AA.
AC S8AEV6;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=THIF-type NAD/FAD binding fold domain-containing protein {ECO:0000259|Pfam:PF00899};
GN ORFNames=H072_6516 {ECO:0000313|EMBL:EPS39681.1};
OS Dactylellina haptotyla (strain CBS 200.50) (Nematode-trapping fungus)
OS (Monacrosporium haptotylum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Orbiliomycetes;
OC Orbiliales; Orbiliaceae; Dactylellina.
OX NCBI_TaxID=1284197 {ECO:0000313|EMBL:EPS39681.1, ECO:0000313|Proteomes:UP000015100};
RN [1] {ECO:0000313|EMBL:EPS39681.1, ECO:0000313|Proteomes:UP000015100}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 200.50 {ECO:0000313|EMBL:EPS39681.1,
RC ECO:0000313|Proteomes:UP000015100};
RX PubMed=24244185;
RA Meerupati T., Andersson K.M., Friman E., Kumar D., Tunlid A., Ahren D.;
RT "Genomic mechanisms accounting for the adaptation to parasitism in
RT nematode-trapping fungi.";
RL PLoS Genet. 9:E1003909-E1003909(2013).
RN [2] {ECO:0000313|Proteomes:UP000015100}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 200.50 {ECO:0000313|Proteomes:UP000015100};
RA Ahren D.G.;
RT "Genomic mechanisms accounting for the adaptation to parasitism in
RT nematode-trapping fungi.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPS39681.1}.
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DR EMBL; AQGS01000457; EPS39681.1; -; Genomic_DNA.
DR RefSeq; XP_011112306.1; XM_011114004.1.
DR AlphaFoldDB; S8AEV6; -.
DR STRING; 1284197.S8AEV6; -.
DR eggNOG; KOG2018; Eukaryota.
DR HOGENOM; CLU_013325_9_3_1; -.
DR OMA; CKLAEYP; -.
DR OrthoDB; 10004at2759; -.
DR Proteomes; UP000015100; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR CDD; cd00755; YgdL_like; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR045886; ThiF/MoeB/HesA.
DR InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR InterPro; IPR035985; Ubiquitin-activating_enz.
DR PANTHER; PTHR43267; TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE; 1.
DR PANTHER; PTHR43267:SF2; TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE 1-RELATED; 1.
DR Pfam; PF00899; ThiF; 1.
DR SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000015100};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 286..534
FT /note="THIF-type NAD/FAD binding fold"
FT /evidence="ECO:0000259|Pfam:PF00899"
FT REGION 1..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 206..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..37
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..58
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 210..262
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 699 AA; 75980 MW; FDC263B2F763661B CRC64;
MSRHDELPPD YTFYSSSSSP FPATALPPSP GAPGAFYPAP PHRSSKTRSK DRDRTFDSEG
AAGTASPSGT KERKHKSRHK PSSSKDIKDT DKPKKKKKRS KKPRESTSSG SEKADSDAES
VMSAFSMQSV SSSLSTFAQS HRAQLAATAL VSGLVVGGTI LGYQTSKRRI RTKMLKDSIA
LTPEHEGEDP MERSIDLSHW LAHSASPASA SRDGPPSYAS ITQPVTPTTI RGAPSNPHAE
QSTPGERPPI TDEQSTALAK HAQSLAAKNK PIPEELILEQ LSRTNSFLGS GGLRTIRSSF
VVIVGLGGVG SWCATMLVRS GIGRVRLIDF DQVTLSSLNR HAVATLEDVG TPKVLAMKKR
LQAVAPWVEI EACSELWTAK DAKRLLDDEP DWVVDAIDNI DTKVDLLAYC HEQRIPVISS
MGAGCKSDPT RILVGDISET TEDPLSKSTR RKLRQRGIAT GITVVYSTEK PGPGKAQLLP
LPDEEHDKGD VSELGVLENF RVRILPVLGT MPATFGLAAA NHVLCKLAEY PLEYLPGQTR
FRPQLYPQVV NQLLAVESRI RNNVPGLKIP ISEADAGYIL EEVFNGKSVV SGLGNRLQLV
RWSPLIGGRF EDGSTGTEGV GPVDEKAVKK KMENIGVGVG GAVSLKLEEL VVMTREEIKI
HEKRVLVGGE SPEAVWGSEV QKLVERKWRE ERPYAQWRE
//
