ID S8FKH4_9BACT Unreviewed; 452 AA.
AC S8FKH4;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Alpha-L-fucosidase {ECO:0000313|EMBL:EPT34388.1};
GN ORFNames=HMPREF9012_0818 {ECO:0000313|EMBL:EPT34388.1};
OS Bacteroidetes bacterium oral taxon 272 str. F0290.
OC Bacteria; Bacteroidota.
OX NCBI_TaxID=888054 {ECO:0000313|EMBL:EPT34388.1, ECO:0000313|Proteomes:UP000015345};
RN [1] {ECO:0000313|EMBL:EPT34388.1, ECO:0000313|Proteomes:UP000015345}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0290 {ECO:0000313|EMBL:EPT34388.1,
RC ECO:0000313|Proteomes:UP000015345};
RA Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M., Haft D.H.,
RA Methe B., Sutton G., Nelson K.E.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC carbohydrate moieties of glycoproteins.
CC {ECO:0000256|ARBA:ARBA00004071}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPT34388.1}.
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DR EMBL; AUTU01000009; EPT34388.1; -; Genomic_DNA.
DR AlphaFoldDB; S8FKH4; -.
DR PATRIC; fig|888054.3.peg.460; -.
DR Proteomes; UP000015345; Unassembled WGS sequence.
DR GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:InterPro.
DR GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR016286; FUC_metazoa-typ.
DR InterPro; IPR000933; Glyco_hydro_29.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR PANTHER; PTHR10030:SF46; ALPHA-L-FUCOSIDASE-RELATED; 1.
DR Pfam; PF01120; Alpha_L_fucos; 1.
DR PIRSF; PIRSF001092; Alpha-L-fucosidase; 1.
DR PRINTS; PR00741; GLHYDRLASE29.
DR SMART; SM00812; Alpha_L_fucos; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000015345};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..32
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 33..452
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004563949"
FT SITE 298
FT /note="May be important for catalysis"
FT /evidence="ECO:0000256|PIRSR:PIRSR001092-1"
SQ SEQUENCE 452 AA; 51878 MW; 9E1A6EBAC1CF0F54 CRC64;
MGISIQSKNI MRIQTLRKGL LAVMLLTATV MAATSFAQSY TTRYEPTREN LKAREEFQDE
KFGIFLHWGI YSMPAQGEWY QNNKNIKCSE YDLFASGFYP SRFNAAEWVS AIKASGAKYI
TITSRHHDGF SMFGTKQSDF NIVDATPFHR DIVKELAVAC QKQDIKLHFY YSHLDWHRPD
YPLGRTGHYT GRPADQQNYD SYFRFMNNQL TELLTNYGPI GAIWFDGLWD HNKDFDWRLD
EQYALIHKLQ PACLIGNNHH RNPYSGEDFQ MFEKDLPGQN TTGFSEGATI SRLPLETCET
MNGMWGYKIE DQNYKTTEEL IRYIVKTAGM NANLLMNIGP QANGELPAVA VQRLKEMGEW
MSQYGETIYG TRGGDVPPHH WGVSTRKGDK LYLHIIDLKD RVLYIPLAAK VKSAVQFIDK
KTVPFKPQEG GILLLLPKVP TEVDYVIELT LK
//
