ID S9TSE1_PAEAL Unreviewed; 801 AA.
AC S9TSE1;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Nitrite reductase [NAD(P)H], large subunit {ECO:0000313|EMBL:EPY05206.1};
GN ORFNames=PAALTS15_21073 {ECO:0000313|EMBL:EPY05206.1};
OS Paenibacillus alvei TS-15.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1117108 {ECO:0000313|EMBL:EPY05206.1, ECO:0000313|Proteomes:UP000015344};
RN [1] {ECO:0000313|EMBL:EPY05206.1, ECO:0000313|Proteomes:UP000015344}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TS-15 {ECO:0000313|EMBL:EPY05206.1,
RC ECO:0000313|Proteomes:UP000015344};
RA Strain E.A., Brown E., Allard M.W., Luo Y.L.;
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRNR:PIRNR037149};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- COFACTOR:
CC Name=siroheme; Xref=ChEBI:CHEBI:60052;
CC Evidence={ECO:0000256|ARBA:ARBA00001929};
CC -!- PATHWAY: Nitrogen metabolism; nitrate reduction (assimilation).
CC {ECO:0000256|ARBA:ARBA00005096}.
CC -!- SIMILARITY: Belongs to the nitrite and sulfite reductase 4Fe-4S domain
CC family. {ECO:0000256|ARBA:ARBA00010429}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPY05206.1}.
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DR EMBL; ATMT01000069; EPY05206.1; -; Genomic_DNA.
DR RefSeq; WP_021261445.1; NZ_ATMT01000069.1.
DR AlphaFoldDB; S9TSE1; -.
DR PATRIC; fig|1117108.3.peg.4346; -.
DR eggNOG; COG1251; Bacteria.
DR UniPathway; UPA00653; -.
DR Proteomes; UP000015344; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:UniProtKB-UniRule.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008942; F:nitrite reductase [NAD(P)H] activity; IEA:UniProtKB-UniRule.
DR GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-UniRule.
DR CDD; cd19943; NirB_Fer2_BFD-like_1; 1.
DR CDD; cd19944; NirB_Fer2_BFD-like_2; 1.
DR Gene3D; 3.30.390.30; -; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 2.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 3.30.413.10; Sulfite Reductase Hemoprotein, domain 1; 1.
DR Gene3D; 3.90.480.10; Sulfite Reductase Hemoprotein;Domain 2; 1.
DR InterPro; IPR007419; BFD-like_2Fe2S-bd_dom.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR016156; FAD/NAD-linked_Rdtase_dimer_sf.
DR InterPro; IPR005117; NiRdtase/SiRdtase_haem-b_fer.
DR InterPro; IPR036136; Nit/Sulf_reduc_fer-like_dom_sf.
DR InterPro; IPR012744; Nitri_red_NirB.
DR InterPro; IPR017121; Nitrite_Rdtase_lsu.
DR InterPro; IPR006067; NO2/SO3_Rdtase_4Fe4S_dom.
DR InterPro; IPR045854; NO2/SO3_Rdtase_4Fe4S_sf.
DR InterPro; IPR006066; NO2/SO3_Rdtase_FeS/sirohaem_BS.
DR InterPro; IPR041575; Rubredoxin_C.
DR NCBIfam; TIGR02374; nitri_red_nirB; 1.
DR PANTHER; PTHR43809; NITRITE REDUCTASE (NADH) LARGE SUBUNIT; 1.
DR PANTHER; PTHR43809:SF1; NITRITE REDUCTASE (NADH) LARGE SUBUNIT; 1.
DR Pfam; PF04324; Fer2_BFD; 2.
DR Pfam; PF01077; NIR_SIR; 1.
DR Pfam; PF03460; NIR_SIR_ferr; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF18267; Rubredoxin_C; 1.
DR PIRSF; PIRSF037149; NirB; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR PRINTS; PR00397; SIROHAEM.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
DR SUPFAM; SSF56014; Nitrite and sulphite reductase 4Fe-4S domain-like; 1.
DR SUPFAM; SSF55124; Nitrite/Sulfite reductase N-terminal domain-like; 1.
DR PROSITE; PS00365; NIR_SIR; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRNR:PIRNR037149};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|PIRNR:PIRNR037149}; Heme {ECO:0000256|ARBA:ARBA00022617};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nitrate assimilation {ECO:0000256|ARBA:ARBA00023063,
KW ECO:0000256|PIRNR:PIRNR037149};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 4..280
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT DOMAIN 316..383
FT /note="NADH-rubredoxin oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18267"
FT DOMAIN 414..463
FT /note="BFD-like [2Fe-2S]-binding"
FT /evidence="ECO:0000259|Pfam:PF04324"
FT DOMAIN 480..530
FT /note="BFD-like [2Fe-2S]-binding"
FT /evidence="ECO:0000259|Pfam:PF04324"
FT DOMAIN 555..617
FT /note="Nitrite/Sulfite reductase ferredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF03460"
FT DOMAIN 626..764
FT /note="Nitrite/sulphite reductase 4Fe-4S"
FT /evidence="ECO:0000259|Pfam:PF01077"
SQ SEQUENCE 801 AA; 88141 MW; 096CA279BC5A6B2C CRC64;
MRKRLVMIGN GMAGARCIEE ILRRDRERYD VTMIGDEPYP NYNRIMLSPV LQGKTTFEEI
TINDWDWYQS NNIHLLTNER VVAIDREAQE VRTDLGTVVP YDELIIATGS SAFILPVPGH
TLEGVVGFRT IKDTKMMLEA AKQYNKAVVI GGGLLGLEAA RGLMNQGMDV HVVHLLPYLM
EMQLDPVAAS LLRRDLEAQG MKFLMEKKTT EIYGDGRVQG LRFEDGTSVE CDLVVMAVGI
RPNVAIAREA GLAVARGIQV NDVMQTSDPA IYAVGECAEH GGIAYGLVAP LYEQGVVLAD
HLTDRPTEGY HGSVLSTQLK VAGCDLFSGG EIHADENTKA IVVQDEFAGA YKKVLVRDGK
VVGVVLYGDV SDGTRLFSML KKESDIQEYT SASVLHKAGE DSGLDVASIS ANETICGCNG
VTKGTIVGAI LENGLTTFDE VKSLTKAGGS CGKCRGMVEA ILAHTLGDKF DASAQKAAGM
CGCTTLSRDE VVAAIREKGL QSPREVRMVL GFTHEEGCSK CRPALNYYLR MLRPETYADD
KASRYVNERM EGNIQNDGTF SVIPRMYGGT TTPEDLIRIG EVAKKYEVPL VKITGASRIG
LYGVKKEDVP KVWEELEMRS GYAYSKSLRN VKSCVGSRFC RFGTQDSLGL GIQLEQEIEM
VDTPHKMKMG VTGCPRNCAE VLTKDFGVVC VENGYQLYFG GNGGTEVREC DSLTTVETEN
EVIRFAKAYV QLYRETGIYG ERTAPWVNRM SADWVRQTLA EEAEVATLVD RFEAAKKTYS
EAWKTALENE ERRSMYTVER P
//
