ID S9VUP6_SCHCR Unreviewed; 1143 AA.
AC S9VUP6;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Smc5-6 complex SMC subunit Smc6 {ECO:0000313|EMBL:EPY49884.1};
GN ORFNames=SPOG_03355 {ECO:0000313|EMBL:EPY49884.1};
OS Schizosaccharomyces cryophilus (strain OY26 / ATCC MYA-4695 / CBS 11777 /
OS NBRC 106824 / NRRL Y48691) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=653667 {ECO:0000313|EMBL:EPY49884.1, ECO:0000313|Proteomes:UP000015464};
RN [1] {ECO:0000313|EMBL:EPY49884.1, ECO:0000313|Proteomes:UP000015464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OY26 / ATCC MYA-4695 / CBS 11777 / NBRC 106824 / NRRL Y48691
RC {ECO:0000313|Proteomes:UP000015464};
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC6 subfamily.
CC {ECO:0000256|ARBA:ARBA00006793}.
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DR EMBL; KE546994; EPY49884.1; -; Genomic_DNA.
DR RefSeq; XP_013025223.1; XM_013169769.1.
DR AlphaFoldDB; S9VUP6; -.
DR STRING; 653667.S9VUP6; -.
DR EnsemblFungi; EPY49884; EPY49884; SPOG_03355.
DR GeneID; 25037672; -.
DR eggNOG; KOG0250; Eukaryota.
DR HOGENOM; CLU_009063_0_0_1; -.
DR OMA; MCHDHFY; -.
DR OrthoDB; 78166at2759; -.
DR Proteomes; UP000015464; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0030915; C:Smc5-Smc6 complex; IEA:EnsemblFungi.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0008094; F:ATP-dependent activity, acting on DNA; IEA:EnsemblFungi.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:EnsemblFungi.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:EnsemblFungi.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR PANTHER; PTHR19306; STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6; 1.
DR PANTHER; PTHR19306:SF6; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6; 1.
DR Pfam; PF02463; SMC_N; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000015464}.
FT DOMAIN 100..1111
FT /note="RecF/RecN/SMC N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02463"
FT REGION 1..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 698..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 334..368
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 425..488
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..71
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 698..718
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1143 AA; 131150 MW; 4D1F40B31FE24225 CRC64;
MSSEQIGDSL YLGNETANNF EENTQGTTRS SPSSPEPPNV KNTKRRRVEH EQNSSSKNTT
LQRSASTTLS RNETIDSIGE DTFQGSNQPN PQFENRVGVI ESIHLVNFMC HDSLRISFGS
RINFVIGHNG SGKSAILTGL TVCLGAKASS TNRAPNMKSL IKQGKSFARI SVTISNRGFE
SYQRDVYGDS ITIERTIRRE GSSEYKLRAH DGTVISTKRE ELDSICDHMG LQIDNPMNIL
TQDTARQFLG NSSPKEKYQL FMKGIQLKQL EDNYSLIEQS LYHTKNALEG KKSGLLHLAK
KEEGCKAKWD QSRETENLHN ILEKKKEEMA WALVVEVEKE LLATEMELQA AEARVNQCNE
ERNLYIKKFG EFDERISLKN QAMESLKSSI TEAKARFEGV IKTFEAHRLE MSDVDLQKRD
IQNSINAAKN CLQIYKDQLA SERERQNNND VSDHQKRLDD ISALQRQIAN LSEQAVELES
KRSELHTTSL EKGGNLSSLL DKKDAIAKQL SDQAEKIRIM EEVQRDKLTA FGKNIPYLLR
LITRETRFQH PPKGPMGRFM TVKEEKWHLT IERILGNVIN GFIVRSHHDQ LILKELMRRA
NCNASIVVGR YDPFDYSSGE PITPYSTVLQ AIHFEDDEVL HTLINHLGIE KMLLIEDRKE
AETYMKRGVV NVTQCYALDP RSKGFGFRIV SNQRSSGISK VTPWNRPPRI GTSNSMDAKR
EQEQLEDLKK LYENANNDLL AAKQEQGKYR REEQIVIEKV EAIKREILDK RRQVNSLESV
ETSVLDTEKI QSLERKISET EKELESYTGQ LQDAKNEERR IVEEQNPVIE EINMFKEKLQ
GENQKLATQQ VEINQIRDER TRLEMAQEEY TNKSDHTLNE MREKEAKRIR CSQVVAEYSA
KAATRCERVP VEHTPQELDN EIERLQLQIT EWRNRTGISV EQAAEDYLKA KEEHDRSKLL
VSKLQLLLET LEETLRKRNE MWAKFRKLIT LRTKELFELY LSQRNFTGKL VIRHQDEFLE
PRVYPANRNL SISRDRQTLS QVSVQGLSGG EKSFATICML LSIWEAMSCP LRCLDEFDVF
MDAVNRLVSI RMMVDSAKDS SEKQFIFITP QDMGQIAFDD DVVVFRLSDP VKSSSALPSS
TAP
//
