ID S9VWS6_SCHCR Unreviewed; 1014 AA.
AC S9VWS6;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=SAGA complex bromodomain subunit Spt7 {ECO:0000313|EMBL:EPY50694.1};
GN ORFNames=SPOG_00764 {ECO:0000313|EMBL:EPY50694.1};
OS Schizosaccharomyces cryophilus (strain OY26 / ATCC MYA-4695 / CBS 11777 /
OS NBRC 106824 / NRRL Y48691) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=653667 {ECO:0000313|EMBL:EPY50694.1, ECO:0000313|Proteomes:UP000015464};
RN [1] {ECO:0000313|EMBL:EPY50694.1, ECO:0000313|Proteomes:UP000015464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OY26 / ATCC MYA-4695 / CBS 11777 / NBRC 106824 / NRRL Y48691
RC {ECO:0000313|Proteomes:UP000015464};
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
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DR EMBL; KE546992; EPY50694.1; -; Genomic_DNA.
DR RefSeq; XP_013024395.1; XM_013168941.1.
DR AlphaFoldDB; S9VWS6; -.
DR STRING; 653667.S9VWS6; -.
DR EnsemblFungi; EPY50694; EPY50694; SPOG_00764.
DR GeneID; 25035096; -.
DR eggNOG; KOG1472; Eukaryota.
DR HOGENOM; CLU_006198_0_1_1; -.
DR OMA; YRRSEAK; -.
DR OrthoDB; 142354at2759; -.
DR Proteomes; UP000015464; Unassembled WGS sequence.
DR GO; GO:0000124; C:SAGA complex; IEA:InterPro.
DR GO; GO:0046695; C:SLIK (SAGA-like) complex; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0040029; P:epigenetic regulation of gene expression; IEA:UniProt.
DR CDD; cd05510; Bromo_SPT7_like; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR006565; BTP.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR037782; Spt7.
DR PANTHER; PTHR47343; TRANSCRIPTIONAL ACTIVATOR SPT7; 1.
DR PANTHER; PTHR47343:SF1; TRANSCRIPTIONAL ACTIVATOR SPT7; 1.
DR Pfam; PF07524; Bromo_TP; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00576; BTP; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Reference proteome {ECO:0000313|Proteomes:UP000015464}.
FT DOMAIN 332..402
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 103..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 232..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 438..532
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 901..921
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 951..974
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 995..1014
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..170
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..255
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 457..473
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 474..532
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1014 AA; 115988 MW; DA332DA4130632C4 CRC64;
MDRNLEDAKT LDEPILHSLA IALLKNEYWS LYLTPEQKRK YINIINDVRL WNRFINVRNW
DTLCDEKDPS GGSEEDEELD MTTLFRCRCM LYDAQINGGL FATRNAEGPS SQVTKENEKD
IPHETQNIEQ SEEEKKNEIE QDSRKKSSTR EINENDYDEP DSDANQPKND EKQEASGASS
RSFVDLESID IDDMDVSGSS TIESSKVLSN IAYNYVYYTL EDDLLDQDEV EKLETDGPSS
PGKASFPQNS SDTSWTENFS QLHSKFGHFT ANFKNLLKYL ENNRNVVGAS DAEIKQLLAD
VRKSRSKWAN EQRIGQEELY EGAEKVIMHL RNYTEHSLPF LTKVSKRDAP DYYNVIKEPM
DLGTMLRKLK ALQYNSKKEI VHDLMLIWSN CLTYNSHPEH PLRAHALIMK KKSQELLNII
PDIVIQSRKD YDETLMEADL ESDEESSEKT SKHTTSKKTS SRGGQSKRSV EVHTDVPNSP
DEGDKQGRKE EDQQKKEESS HLPPSSEFAE IPEEKRSAEE ENTARAQNEI EDKVVSDVAH
EFWKNNSKSR RFECIMRNRN MLGNLNAVEN PSLSCRSPEA MTSFMNREKA YEKFSARSES
LSGILDVSNL SSNYDSLFEY DVASGVPVHY FAESNVGPTE DGVFNNYLLW EMNHQSPGLS
SSIYKNISKM QQIRKLCNKI QTVRQMQLPQ PFYSDYYRSN IPFANEESIL LDVPQNFEEV
SDFQPVAHGI LKKLCSVILF HAGFDSFHSE ALNALTDVAA DYMKNAGTLM KKYLSEKQKD
SKEEIINQTL QELGVSGPET LVSYVFDDIK RYGIKLDEVH QRLHRHLVEL LRPALSTTND
EEEIFGRDSD SFITGGFSYD TGDDFFGLRE LGLEKELGLD SLSVPLHLLQ SRLRLNMSQQ
PELTTENTKE YPPAPRYPPI TRESLKDEIG LIQGFLSSRM DEFGLNELIE DEDIRPRNKP
PRPRLPPNGK ITTGRKRIAS SVFLNQSLRK KKCLKNAEVS QSNEMPSTVQ EEKA
//
