ID S9WLB7_CAMFR Unreviewed; 552 AA.
AC S9WLB7;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=CABIT domain-containing protein {ECO:0000259|Pfam:PF12736};
GN ORFNames=CB1_001328020 {ECO:0000313|EMBL:EPY77038.1};
OS Camelus ferus (Wild bactrian camel) (Camelus bactrianus ferus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus.
OX NCBI_TaxID=419612 {ECO:0000313|EMBL:EPY77038.1, ECO:0000313|Proteomes:UP000030684};
RN [1] {ECO:0000313|EMBL:EPY77038.1, ECO:0000313|Proteomes:UP000030684}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=bactrian camel {ECO:0000313|Proteomes:UP000030684};
RX PubMed=23149746;
RG Bactrian Camels Genome Sequencing and Analysis Consortium;
RA Jirimutu, Wang Z., Ding G., Chen G., Sun Y., Sun Z., Zhang H., Wang L.,
RA Hasi S., Zhang Y., Li J., Shi Y., Xu Z., He C., Yu S., Li S., Zhang W.,
RA Batmunkh M., Ts B., Narenbatu, Unierhu, Bat-Ireedui S., Gao H.,
RA Baysgalan B., Li Q., Jia Z., Turigenbayila, Subudenggerile, Narenmanduhu,
RA Wang Z., Wang J., Pan L., Chen Y., Ganerdene Y., Dabxilt, Erdemt, Altansha,
RA Altansukh, Liu T., Cao M., Aruuntsever, Bayart, Hosblig, He F., Zha-ti A.,
RA Zheng G., Qiu F., Sun Z., Zhao L., Zhao W., Liu B., Li C., Chen Y.,
RA Tang X., Guo C., Liu W., Ming L., Temuulen, Cui A., Li Y., Gao J., Li J.,
RA Wurentaodi, Niu S., Sun T., Zhai Z., Zhang M., Chen C., Baldan T.,
RA Bayaer T., Li Y., Meng H.;
RT "Genome sequences of wild and domestic bactrian camels.";
RL Nat. Commun. 3:1202-1202(2012).
CC -!- SIMILARITY: Belongs to the GAREM family.
CC {ECO:0000256|ARBA:ARBA00006392}.
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DR EMBL; KB017525; EPY77038.1; -; Genomic_DNA.
DR AlphaFoldDB; S9WLB7; -.
DR Proteomes; UP000030684; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd01867; Rab8_Rab10_Rab13_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR025946; CABIT_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR14454:SF5; GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN 2; 1.
DR PANTHER; PTHR14454; GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN FAMILY MEMBER; 1.
DR Pfam; PF12736; CABIT; 2.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00177; ARF; 1.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00176; RAN; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
DR PROSITE; PS51420; RHO; 1.
PE 3: Inferred from homology;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030684}.
FT DOMAIN 214..263
FT /note="CABIT"
FT /evidence="ECO:0000259|Pfam:PF12736"
FT DOMAIN 262..388
FT /note="CABIT"
FT /evidence="ECO:0000259|Pfam:PF12736"
SQ SEQUENCE 552 AA; 61198 MW; B8CED5B14B8CB27F CRC64;
MAKKTYDLLF KLLLIGDSGV GKTCVLFRFS DDAFNTTFIS TIGIDFKIKT VELQGKKIKL
QIWDTAGQER FHTITTSYYR GAMGIMLVYD ITNGKSFENI SKWLRNIDEH ANEDVERMLL
GNKCDMDDKR VVPKGKGEQI AREHGIRFFE TSAKANINIE KAFLTLAEDI LRKTPVKEPN
SENVDISSGG GGCAAGLGSN RAQVDLEDVV SRSTGEYAEG VSERDILLIH SCRQWTTVTA
HTLEEGHYVI GPKIDIPLQY PGEYAEGVSE RDILLIHSCR QWTTVTAHTL EEGHYVIGPK
IDIPLQYPGK FKLLEQARDV REPVRYFSSV EEVASVFPDR IFVMEAITFS VKVVSGEFSE
DSEVYNFTLH AGDELTLMGQ AEILSSLSYY SSGLQDGAGS RSGSGSPSPD AYSLYCYPCT
WGDCKPSHPQ KRFAPFGALN PFSGPAYPTG PSEPAPEPFD PFELGQGSSP EPELLRCQEP
RAVGAPGPGL SPLGSPKAFE PEEDVVSFFA RERIDGSIFV QLSEDILADD FHLTKLQVKK
IMQFIKGWRP KI
//
