ID S9WZ52_SCHCR Unreviewed; 750 AA.
AC S9WZ52;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=PX/PXA domain-containing protein {ECO:0000313|EMBL:EPY49982.1};
GN ORFNames=SPOG_03451 {ECO:0000313|EMBL:EPY49982.1};
OS Schizosaccharomyces cryophilus (strain OY26 / ATCC MYA-4695 / CBS 11777 /
OS NBRC 106824 / NRRL Y48691) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=653667 {ECO:0000313|EMBL:EPY49982.1, ECO:0000313|Proteomes:UP000015464};
RN [1] {ECO:0000313|EMBL:EPY49982.1, ECO:0000313|Proteomes:UP000015464}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OY26 / ATCC MYA-4695 / CBS 11777 / NBRC 106824 / NRRL Y48691
RC {ECO:0000313|Proteomes:UP000015464};
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KE546994; EPY49982.1; -; Genomic_DNA.
DR RefSeq; XP_013025320.1; XM_013169866.1.
DR AlphaFoldDB; S9WZ52; -.
DR STRING; 653667.S9WZ52; -.
DR EnsemblFungi; EPY49982; EPY49982; SPOG_03451.
DR GeneID; 25037768; -.
DR eggNOG; ENOG502RM76; Eukaryota.
DR HOGENOM; CLU_371373_0_0_1; -.
DR OMA; FVNRCII; -.
DR OrthoDB; 2727031at2759; -.
DR Proteomes; UP000015464; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR036871; PX_dom_sf.
DR PANTHER; PTHR22775:SF47; MEIOTICALLY UP-REGULATED GENE 122 PROTEIN; 1.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR Pfam; PF02194; PXA; 1.
DR SMART; SM00313; PXA; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS51207; PXA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000015464};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 93..266
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT REGION 500..527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..526
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 750 AA; 85391 MW; FDDA3314A409436F CRC64;
MFMQWNLSKA GKAFLSLENK SSYVFIFSLC LISFYVLHVF FGRFVYFAIG IFVGVSFQGL
VQKNGNIILN IKHPNIEDPS QYVPQRYPQH ALPEELEAPL LLLITKLTHH YIYGWYKQVS
YDNSFVTEVE STIGYIFRNF YSYLSTQDSS YLIFEMVKNV LNTITFLLSD LNMFLSKKMP
ITEFAVRYPN SAVAKMLDKA ANEQALRAQA SAMVTKFCKP EDAACLPLHV LLREVLAMQV
FKKITTHCAK PRFVNRCIIL FLSPSKEKDE CLDKKTYINR CLLNQTLKDT SSSATLPTGG
AQASSSYNNA LFEAEINIQY RSLEPKDLSS PIKDKKNLKF VITVHPLYLD IPPWIVYRPY
TSLKSLYKDI RKEYLHALGT PLKIPEWRAQ TYGHLQRELS AFLNLIVQNA QLSNNVAVRK
FFCKSMSFEP LSDDVVDDME KQKNSSLSAV SHKLLGVTKI VSNKSGKSSH SKESEGSSNV
EVSWKTKFEK SMLEDTELSK LPSNDVSSLE DDNQSFENKD EEKNGSMFSE SNLYVDENSA
FNIQEETLKE IINSGFALFG EISCLNPKTW FFRRTVLSVL KSLLMHGPLD FSGLVEKMLK
DHVFAKLSNT QLVGDLFTSL ILSIWPEEKE KVQEHLKNLN KDCAGDNERG ADWNPSSMSK
DNDELYLEEA LKNSLFFSHS EFAVSEESDD EIREQAQELF LNNEYSDSAS LLGPFTSEDS
LRLLFDLLQE SDLVEGFLAH VLSNALHSII
//
