ID S9XK74_CAMFR Unreviewed; 2009 AA.
AC S9XK74;
DT 16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT 16-OCT-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Trinucleotide repeat-containing gene 6B protein isoform 1 {ECO:0000313|EMBL:EPY88553.1};
GN ORFNames=CB1_000168045 {ECO:0000313|EMBL:EPY88553.1};
OS Camelus ferus (Wild bactrian camel) (Camelus bactrianus ferus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus.
OX NCBI_TaxID=419612 {ECO:0000313|EMBL:EPY88553.1, ECO:0000313|Proteomes:UP000030684};
RN [1] {ECO:0000313|EMBL:EPY88553.1, ECO:0000313|Proteomes:UP000030684}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=bactrian camel {ECO:0000313|Proteomes:UP000030684};
RX PubMed=23149746;
RG Bactrian Camels Genome Sequencing and Analysis Consortium;
RA Jirimutu, Wang Z., Ding G., Chen G., Sun Y., Sun Z., Zhang H., Wang L.,
RA Hasi S., Zhang Y., Li J., Shi Y., Xu Z., He C., Yu S., Li S., Zhang W.,
RA Batmunkh M., Ts B., Narenbatu, Unierhu, Bat-Ireedui S., Gao H.,
RA Baysgalan B., Li Q., Jia Z., Turigenbayila, Subudenggerile, Narenmanduhu,
RA Wang Z., Wang J., Pan L., Chen Y., Ganerdene Y., Dabxilt, Erdemt, Altansha,
RA Altansukh, Liu T., Cao M., Aruuntsever, Bayart, Hosblig, He F., Zha-ti A.,
RA Zheng G., Qiu F., Sun Z., Zhao L., Zhao W., Liu B., Li C., Chen Y.,
RA Tang X., Guo C., Liu W., Ming L., Temuulen, Cui A., Li Y., Gao J., Li J.,
RA Wurentaodi, Niu S., Sun T., Zhai Z., Zhang M., Chen C., Baldan T.,
RA Bayaer T., Li Y., Meng H.;
RT "Genome sequences of wild and domestic bactrian camels.";
RL Nat. Commun. 3:1202-1202(2012).
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DR EMBL; KB016463; EPY88553.1; -; Genomic_DNA.
DR Proteomes; UP000030684; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR GO; GO:0044281; P:small molecule metabolic process; IEA:UniProt.
DR CDD; cd03302; Adenylsuccinate_lyase_2; 1.
DR CDD; cd12712; RRM_TNRC6B; 1.
DR Gene3D; 1.10.275.60; -; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 6.10.250.1570; -; 1.
DR Gene3D; 1.20.200.10; Fumarase/aspartase (Central domain); 2.
DR InterPro; IPR019468; AdenyloSucc_lyase_C.
DR InterPro; IPR020557; Fumarate_lyase_CS.
DR InterPro; IPR022761; Fumarate_lyase_N.
DR InterPro; IPR008948; L-Aspartase-like.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR032226; TNRC6_PABC-bd.
DR InterPro; IPR034925; TNRC6B_RRM.
DR PANTHER; PTHR13020; TRINUCLEOTIDE REPEAT-CONTAINING GENE 6; 1.
DR PANTHER; PTHR13020:SF32; TRINUCLEOTIDE REPEAT-CONTAINING GENE 6B PROTEIN; 1.
DR Pfam; PF10397; ADSL_C; 1.
DR Pfam; PF00206; Lyase_1; 1.
DR Pfam; PF16608; TNRC6-PABC_bdg; 1.
DR SMART; SM00998; ADSL_C; 1.
DR SUPFAM; SSF48557; L-aspartase-like; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS00163; FUMARATE_LYASES; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030684};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT DOMAIN 1927..2009
FT /note="Adenylosuccinate lyase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00998"
FT REGION 20..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 91..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 191..926
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 943..963
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1093..1131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1433..1456
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..242
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 250..272
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..300
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..340
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 348..375
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 390..406
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 417..436
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..500
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..575
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 588..618
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 620..636
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 638..732
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 739..757
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 793..810
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 811..838
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 882..899
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1093..1113
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2009 AA; 215102 MW; 79793A404F4816B9 CRC64;
MSLVANTGML GSLFRSTVTE QKTKVPEVTK PSLSQPTAAS PIGSSPSPPV NGGNNAKRVA
VPNGQPPSAA RYMPREVPPR FRCQQDHKVL LKRGQPPPPS CMLLGGGAGP PPSTAPGANP
NNAQVTGTLL QSESGTAPES TLGGAAASNY ANSTWGPGAS SNNGASPNPI HIWDKVIVDG
SDMEEWPCIA SKDTESSSEN TTDNNSASNP GSEKSTLPGS TTSNKGKGSQ CQSASSGNEC
NLGVWKSDPK AKSVQSSNST TESNNGLGNW RNVSGQDRIG PGSGFSNFNP NSNPSAWPAL
VQEGNSRKGA LETDTSNPSA QVSTVGQASR EQQSKMENAG VNFVVSGREQ AQIHNTDGPK
NGNTNSLNLS SPNPMENKGM PFGMGLGNAS RSTDAPSQST GDRKTGSVGS WGAARGPSGT
DTASGQSNSG NNGNNGKDRE DSWKGASVQK STGSKNDSWD NSNRSTGGSW NFGPQDSNDN
KWGEGNKMTS GVSQGEWKQP TGSDELKIGE WSGPNQPNSS TGAWDNQKGH PLPENQGNAQ
APCWGRSSSS TGSEVGGQST GSNHKAGSSD SHNSGRRSYR PTHPDCQAVL QTLLSRTDLD
PRVLSNTGWG QTQIKQDTVW DIEEVPRPEG KSDKGTEGWE SAATQTKNSG GWGDAPSQSN
QMKSGWGELS ASTEWKDPKN TGGWNDYKNN NSSNWGGGRP DEKTSSSWNE NSSKDQGWGG
GRQPNQGWTS GKNGWGEEVD QAKNSNWESS ASKPVSGWGE GGQNEIGTWG NGGSASLASK
GGWEDCKRSP AWTETGRQPN SWNKQHQQQQ QPQQPPPPQP EASGSWGGPA PPPPGNGRPS
NSSWSSGPQP VTPKDEEPSG WEEPSPQSIS RKMDIDDGTS AWGDPNSYNY KNVNLWDKNS
QGGPAPREPN LPTPMTGKSA SGSLPEKKFD VDKRAMNLGD FNDIMRKDRP GFRPPNSKDM
GTTDSGPYFE KGGNHGLFGN STAQSRGVHT PVQPLNSSPN LRAQVPPQFI SPQVSASMLK
QFPNSGLNPG LFNVGPQLSP QQIAMLSQLP QIPQFQLACQ LLLQQQQQQQ LLQNQRKLSQ
AVRQQQEQQL ARMVSALQQQ QQQQQQQPSM KHSPSHPVGP KPHLDNMVPN ALNVGLPDLQ
TKGPIPGYGS GFSSGGMDYG MVGGKEAGTE SRFKQWTSMM EGLPSVATQE ASLHKNGAIV
APGKTRGGSP YNQFDIIPGD TLGGHTGPAG DSWLPAKSPP TNKIGSKSSN ASWPPEFQPG
VPWKGIQNID PESDPYVTPG SVLGGTATSP IVDTDHQLLR DNTTGSNSSL NTSLPSPGAW
PYSASDNSFT NVHSTSASTW SDGGSVRPSY WLVLHNLTPQ IDGSTLRTIC MQHGPLLTFH
LNLTQGTALI RYSTKQEAAK AQTALHMCVL GNTTILAEFA TDDEVSRFLA QAQPPTPAAT
PNAPAAGWQS LETGQTQPDP VGPALNLFAA RQLPASFASV KLRVAVRSEV SDPGEPAASS
LSSQKRFADL ACDEQIQEMK SNLDNIDFKM AAEEEKRLRH DVMAHVHTFA HCCPKAAGII
HLGATSCYVG DNTDLIILRN AFDLLLPKQK PEETVNVKES VLGVCGLAMV DVAFCAGSLH
TQSHCVEAPL LHLLERVQQA FVVQQASSIH LGWCNERRLL PQLAGIRNAG NDVGPAQLTT
VGKRCCLWIQ DLCMDLQNLK RVRDDLRFRG VKGTTGTQAS FLQLFEGDDQ KVEQLDKMVT
EKAGFKRAFI ITGQTYTRKV DIEVLSVLAS LGASVHKLSS GTAEELASFT SVVLASRAPL
LRVWVLPVPP LFPQICTDIR LLANLKEMEE PFEKQQIGSS AMPYKRNPMR SERCCSLARH
LMILVTDPLQ TASVQWFERT LDDSANRRIC LAEAFLTADT ILNTLQNISE GLVVYPKVIE
RRIRQELPFM ATENIIMAMV KAGGNRQDCH EKIRVLSQQA AAVVKQEGGD NDLIERIQAD
AYFSPIHSQL DHLLDPSTFT GRASQQPVA
//
